| Literature DB >> 2283726 |
H Shimizu1, H Tsuchie, H Honma, K Yoshida, T Tsuruoka, H Ushijima, T Kitamura.
Abstract
The effect of N-(3-phenyl-2-propenyl)-1-deoxynojirimycin (ppDNM) on the lectin binding to HIV-1 glycoprotein was analyzed by using biotinylated lectins of various sugar specificities as probes. ppDNM potentially inhibited HIV-1-induced syncytium formation and viral infectivity of HIV-1 without cytotoxicity. The lectin binding assay showed that ppDNM treatment reduced Con A binding to gp120 of HIV-1.Entities:
Mesh：
Substances：
Year: 1990 PMID： 2283726 DOI： 10.7883/yoken1952.43.75
Source DB: PubMed Journal: Jpn J Med Sci Biol ISSN： 0021-5112