| Literature DB >> 22836612 |
Magdalena Arazna1, Michal P Pruchniak, Katarzyna Zycinska, Urszula Demkow.
Abstract
NETosis is a unique death pathway that differs from apoptosis and necrosis and depends on the generation of reactive oxygen species (ROS) by NADPH oxidase. During this process, neutrophil extracellular traps (NETs) are created. NETs are extracellular structures composed of chromatin and variety of proteins from cells granules that bind and kill microorganisms. Recently, novel functions of NET have been proposed. It seems that neutrophil traps play an essential role during autoimmunity. They can induce and exacerbate diseases based on immune system malfunction.Entities:
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Year: 2013 PMID： 22836612 DOI： 10.1007/978-94-007-4549-0_1
Source DB: PubMed Journal: Adv Exp Med Biol ISSN： 0065-2598 Impact factor: 2.622