| Literature DB >> 22835460 |
Abstract
Transforming growth factor-β (TGF-β) isoforms are profibrotic cytokines, par excellence, and have complex multifunctional effects on many systems, depending on the biologic setting. Retinoids are vitamin A derivatives that also have diverse effects in development, physiology, and disease. The interactions between these classes of molecules are, not surprisingly, highly complex and are dependent on the tissue, cellular, and molecular settings.Entities:
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Year: 2012 PMID: 22835460 PMCID: PMC3407374 DOI: 10.1016/j.semnephrol.2012.04.008
Source DB: PubMed Journal: Semin Nephrol ISSN: 0270-9295 Impact factor: 5.299