| Literature DB >> 22834418 |
Cun-Qin Wang1, Lei Wang, Chun-Lin Fan, Dong-Mei Zhang, Xiao-Jun Huang, Ren-Wang Jiang, Liang-Liang Bai, Jun-Min Shi, Ying Wang, Wen-Cai Ye.
Abstract
Two unusual triterpenes, ilelic acids A (1) and B (2), together with their biosynthetic related compounds ilelic acids C (3) and D (4) were isolated from the leaves of Ilex latifolia. Their structures with absolute configurations were elucidated by spectroscopic analysis and modified Mosher's method. The plausible biogenetic pathway of 1 and 2 is proposed. These triterpenes exhibited a potent inhibitory effect on MCF-7 and MDA-MB-231 cells.Entities:
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Year: 2012 PMID： 22834418 DOI： 10.1021/ol301745b
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005