Literature DB >> 22833898

Decreased blood-brain barrier expression of P-glycoprotein in Alzheimer's disease: impact on pathogenesis and brain access of therapeutic agents.

Joseph A Nicolazzo, William A Banks.   

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Year:  2011        PMID: 22833898     DOI: 10.4155/tde.11.65

Source DB:  PubMed          Journal:  Ther Deliv        ISSN: 2041-5990


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  4 in total

1.  Evaluation of [18F]MC225 as a PET radiotracer for measuring P-glycoprotein function at the blood-brain barrier in rats: Kinetics, metabolism, and selectivity.

Authors:  Heli Savolainen; Albert D Windhorst; Philip H Elsinga; Mariangela Cantore; Nicola A Colabufo; Antoon Tm Willemsen; Gert Luurtsema
Journal:  J Cereb Blood Flow Metab       Date:  2016-01-01       Impact factor: 6.200

Review 2.  Neurovascular Alterations in Alzheimer's Disease: Transporter Expression Profiles and CNS Drug Access.

Authors:  Mitchell P McInerney; Jennifer L Short; Joseph A Nicolazzo
Journal:  AAPS J       Date:  2017-05-01       Impact factor: 4.009

3.  Increasing Intracellular Levels of Iron with Ferric Ammonium Citrate Leads to Reduced P-glycoprotein Expression in Human Immortalised Brain Microvascular Endothelial Cells.

Authors:  Stephanie A Newman; Yijun Pan; Jennifer L Short; Joseph A Nicolazzo
Journal:  Pharm Res       Date:  2021-02-02       Impact factor: 4.200

4.  Intestinal Permeability and Oral Absorption of Selected Drugs Are Reduced in a Mouse Model of Familial Alzheimer's Disease.

Authors:  Liang Jin; Yijun Pan; Natalie Lan Linh Tran; Leon N Polychronopoulos; Aparna Warrier; Kim L R Brouwer; Joseph A Nicolazzo
Journal:  Mol Pharm       Date:  2020-04-08       Impact factor: 4.939

  4 in total

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