BACKGROUND: One of the most important concerns about systemic lupus erythematosus (SLE) is the presence of oral lesions, which in turn is one of the diagnostic criteria for SLE. Regarding the wide range of oral lesions and the absence of comprehensive data in Iran, this study aimed to evaluate the prevalence of oral mucosal lesions and related factors in patients with SLE at three rheumatology clinics in Tehran. METHODS: This descriptive study was performed on 188 patients by observation, clinical examination, completing questionnaire and also evaluating patients' medical records. The lesions explored were ulcer, erythema, erythematous center with white striae or spots, and white plaques. Related factors taken into consideration were age, sex, smoking, frequency of pregnancy, oral health status, duration of disease, medications taken daily dosage of corticosteroid drugs, and the state of disease control. Sampling was done by the continuous method and data obtained were analyzed by SPSS version 16.0 and ordinal regression tests. FINDINGS: Out of 188 patients, 102 (54.3%) patients had oral mucosal lesions. The most prevalent lesion was ulcer (28.1%) and the most common region involved was the buccal and labial mucosa. CONCLUSION: With regard to the high prevalence of oral mucosal lesions in patients with SLE, it is of paramount importance to emphasize early detection of these lesions as a mean of diagnosis of disease and faster initiation of treatment.
BACKGROUND: One of the most important concerns about systemic lupus erythematosus (SLE) is the presence of oral lesions, which in turn is one of the diagnostic criteria for SLE. Regarding the wide range of oral lesions and the absence of comprehensive data in Iran, this study aimed to evaluate the prevalence of oral mucosal lesions and related factors in patients with SLE at three rheumatology clinics in Tehran. METHODS: This descriptive study was performed on 188 patients by observation, clinical examination, completing questionnaire and also evaluating patients' medical records. The lesions explored were ulcer, erythema, erythematous center with white striae or spots, and white plaques. Related factors taken into consideration were age, sex, smoking, frequency of pregnancy, oral health status, duration of disease, medications taken daily dosage of corticosteroid drugs, and the state of disease control. Sampling was done by the continuous method and data obtained were analyzed by SPSS version 16.0 and ordinal regression tests. FINDINGS: Out of 188 patients, 102 (54.3%) patients had oral mucosal lesions. The most prevalent lesion was ulcer (28.1%) and the most common region involved was the buccal and labial mucosa. CONCLUSION: With regard to the high prevalence of oral mucosal lesions in patients with SLE, it is of paramount importance to emphasize early detection of these lesions as a mean of diagnosis of disease and faster initiation of treatment.
Authors: Pongsawat Rodsaward; Titipong Prueksrisakul; Tawatchai Deekajorndech; Steven W Edwards; Michael W Beresford; Direkrit Chiewchengchol Journal: Am J Clin Dermatol Date: 2017-12 Impact factor: 7.403
Authors: Adrià Aterido; Antonio Julià; Patricia Carreira; Ricardo Blanco; José Javier López-Longo; José Javier Pérez Venegas; Àlex Olivé; José Luís Andreu; Maria Ángeles Aguirre-Zamorano; Paloma Vela; Joan M Nolla; José Luís Marenco-de la Fuente; Antonio Zea; José María Pego; Mercedes Freire; Elvira Díez; María López-Lasanta; Mireia López-Corbeto; Núria Palau; Raül Tortosa; Josep Lluís Gelpí; Devin Absher; Richard M Myers; Antonio Fernández-Nebro; Sara Marsal Journal: Arthritis Res Ther Date: 2017-06-15 Impact factor: 5.156
Authors: Tom Dudding; Simon Haworth; Penelope A Lind; J Fah Sathirapongsasuti; Joyce Y Tung; Ruth Mitchell; Lucía Colodro-Conde; Sarah E Medland; Scott Gordon; Benjamin Elsworth; Lavinia Paternoster; Paul W Franks; Steven J Thomas; Nicholas G Martin; Nicholas J Timpson Journal: Nat Commun Date: 2019-03-05 Impact factor: 14.919