PURPOSE: To assess the seroprevalence and seroconversion of Epstein-Barr virus (EBV) and cytomegalovirus (CMV) Immunoglobulin G (IgG) antibodies and identify associated socioeconomic and smoking variables among male young adults in Israel, to explore health disparities and aid prevention efforts. METHODS: A population-based seroprevalence study of EBV and CMV IgG antibodies in a systematic sample of Israeli males upon recruitment to mandatory military service during 1994-2004. Associations between socioeconomic and smoking variables and the seroprevalence of EBV/CMV were evaluated, controlling for possible confounders. A subset of seronegative subjects was assessed for seroconversion upon discharge from military service. RESULTS: Overall seroprevalence rates were 87% for EBV and 59% for CMV. An association between the seroprevalence of EBV and CMV was observed. Seroconversion was 56% for EBV as compared with 31% for CMV. Lower paternal education was found to be associated with both EBV and CMV seroprevalence. Lower socioeconomic status, North African origin, and urban residence were found to be associated with CMV seropositivity, as was smoking for EBV seropositivity. CONCLUSIONS: Socioeconomic disparities exist in the seroprevalence rates of CMV and EBV among Israeli male young adults. The results of the study could aid public health efforts and determine target populations when a vaccine becomes available.
PURPOSE: To assess the seroprevalence and seroconversion of Epstein-Barr virus (EBV) and cytomegalovirus (CMV) Immunoglobulin G (IgG) antibodies and identify associated socioeconomic and smoking variables among male young adults in Israel, to explore health disparities and aid prevention efforts. METHODS: A population-based seroprevalence study of EBV and CMV IgG antibodies in a systematic sample of Israeli males upon recruitment to mandatory military service during 1994-2004. Associations between socioeconomic and smoking variables and the seroprevalence of EBV/CMV were evaluated, controlling for possible confounders. A subset of seronegative subjects was assessed for seroconversion upon discharge from military service. RESULTS: Overall seroprevalence rates were 87% for EBV and 59% for CMV. An association between the seroprevalence of EBV and CMV was observed. Seroconversion was 56% for EBV as compared with 31% for CMV. Lower paternal education was found to be associated with both EBV and CMV seroprevalence. Lower socioeconomic status, North African origin, and urban residence were found to be associated with CMV seropositivity, as was smoking for EBV seropositivity. CONCLUSIONS: Socioeconomic disparities exist in the seroprevalence rates of CMV and EBV among Israeli male young adults. The results of the study could aid public health efforts and determine target populations when a vaccine becomes available.
Authors: Gabriella M Lawrence; Yehiel Friedlander; Ronit Calderon-Margalit; Daniel A Enquobahrie; Jonathan Yinhao Huang; Russell P Tracy; Orly Manor; David S Siscovick; Hagit Hochner Journal: BMJ Open Date: 2017-12-21 Impact factor: 2.692
Authors: Martina Taborelli; Maurizio Montella; Massimo Libra; Rosamaria Tedeschi; Anna Crispo; Maria Grimaldi; Luigino Dal Maso; Diego Serraino; Jerry Polesel Journal: BMC Cancer Date: 2017-06-16 Impact factor: 4.430
Authors: Joanne R Winter; Charlotte Jackson; Joanna Ea Lewis; Graham S Taylor; Olivia G Thomas; Helen R Stagg Journal: J Glob Health Date: 2020-06 Impact factor: 4.413
Authors: Joanne R Winter; Graham S Taylor; Olivia G Thomas; Charlotte Jackson; Joanna E A Lewis; Helen R Stagg Journal: BMC Infect Dis Date: 2019-11-28 Impact factor: 3.090
Authors: Joanne R Winter; Graham S Taylor; Olivia G Thomas; Charlotte Jackson; Joanna E A Lewis; Helen R Stagg Journal: BMC Infect Dis Date: 2020-11-23 Impact factor: 3.090