Literature DB >> 22829245

Prevalence of psychotropic drug use in adults with intellectual disability: positive and negative findings from a large scale study.

John A Tsiouris1, Soh-Yule Kim, W Ted Brown, Jill Pettinger, Ira L Cohen.   

Abstract

The use of psychotropics by categories and the reason for their prescription was investigated in a large scale study of 4,069 adults with ID, including those with autism spectrum disorder, in New York State. Similar to other studies it was found that 58 % (2,361/4,069) received one or more psychotropics. Six percent received typical, while 39 % received atypical antipsychotics [corrected]. There was greater use of antidepressants (23 %), mood stabilizers (19 %), and antianxiety agents (16 %) relative to other studies. The use of anti-impulsives, stimulants and hypnotics was rare (1-2 %). Half of the psychotropics were prescribed for treatment of major psychiatric disorders, 13 % for control of challenging behaviors, and 38 % for both. Results indicated that the major psychiatric disorders, except anxiety disorder and autism, influenced the use of psychotropics and the number of medication used. These findings imply that although practitioners still rely too heavily on the use of antipsychotics in this population, there is a welcome shift in the prescription patterns relative to other studies. The practitioners appeared to use psychotropics primarily to treat diagnosed psychiatric disorders and not just to control aggressive behavior which suggests that evidence-based practice of psychiatry is playing an increasing role in the ID population.

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Year:  2013        PMID: 22829245     DOI: 10.1007/s10803-012-1617-6

Source DB:  PubMed          Journal:  J Autism Dev Disord        ISSN: 0162-3257


  51 in total

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4.  Association of aggressive behaviours with psychiatric disorders, age, sex and degree of intellectual disability: a large-scale survey.

Authors:  J A Tsiouris; S Y Kim; W T Brown; I L Cohen
Journal:  J Intellect Disabil Res       Date:  2011-04-15

5.  Psychotropic medication use among children with autism spectrum disorders enrolled in a national registry, 2007-2008.

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Journal:  J Autism Dev Disord       Date:  2010-03

6.  International guide to prescribing psychotropic medication for the management of problem behaviours in adults with intellectual disabilities.

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Journal:  World Psychiatry       Date:  2009-10       Impact factor: 49.548

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Review 8.  Representation of people with intellectual disabilities in randomised controlled trials on antipsychotic treatment for behavioural problems.

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Journal:  J Intellect Disabil Res       Date:  2010-12-13

9.  Adults with intellectual disabilities: prevalence, incidence and remission of self-injurious behaviour, and related factors.

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10.  The use of anti-psychotic drugs with adults with learning disabilities and challenging behaviour.

Authors:  C Kiernan; D Reeves; A Alborz
Journal:  J Intellect Disabil Res       Date:  1995-08
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  28 in total

Review 1.  Polypharmacy in the treatment of subjects with intellectual disability.

Authors:  Frank Häβler; Johannes Thome; Olaf Reis
Journal:  J Neural Transm (Vienna)       Date:  2014-05-25       Impact factor: 3.575

Review 2.  Medication use and potentially inappropriate prescribing in older adults with intellectual disabilities: a neglected area of research.

Authors:  Maire O'Dwyer; Philip McCallion; Mary McCarron; Martin Henman
Journal:  Ther Adv Drug Saf       Date:  2018-06-20

3.  Cognitive Behavioral Therapy for Depressed Adults with Mild Intellectual Disability: A Pilot Study.

Authors:  Sigan L Hartley; Anna J Esbensen; Rebecca Shalev; Lori B Vincent; Iulia Mihaila; Paige Bussanich
Journal:  J Ment Health Res Intellect Disabil       Date:  2015-04-06

4.  [Determinants of psychotropic medication in adults with mild or moderate intellectual disabilities].

Authors:  M Schützwohl; E Voss; M Stiawa; H-J Salize; B Puschner; A Koch
Journal:  Nervenarzt       Date:  2017-11       Impact factor: 1.214

Review 5.  Pharmacological management of behavioral and psychiatric symptoms in older adults with intellectual disability.

Authors:  Nicole Eady; Ken Courtenay; André Strydom
Journal:  Drugs Aging       Date:  2015-02       Impact factor: 3.923

6.  Mental illness, problem behaviour, needs and service use in adults with intellectual disability.

Authors:  Matthias Schützwohl; Andrea Koch; Nadine Koslowski; Bernd Puschner; Elke Voß; Hans Joachim Salize; Andrea Pfennig; Anke Vogel
Journal:  Soc Psychiatry Psychiatr Epidemiol       Date:  2016-03-07       Impact factor: 4.328

7.  Social Communication is an Emerging Target for Pharmacotherapy in Autism Spectrum Disorder - A Review of the Literature on Potential Agents.

Authors:  Danielle A Baribeau; Evdokia Anagnostou
Journal:  J Can Acad Child Adolesc Psychiatry       Date:  2014-02

8.  Assessing the Impact of Psychotropic Medication Changes on Challenging Behavior of Individuals with Intellectual Disabilities.

Authors:  Maria G Valdovinos; Meara Henninger-McMahon; Elizabeth Schieber; Lisa Beard; Brenna Conley; Annette Haas
Journal:  Int J Dev Disabil       Date:  2016-04-28

9.  Antipsychotic Use and Metabolic Monitoring in Individuals with Developmental Disabilities Served in a Medicaid Medical Home.

Authors:  Lisa M Ruiz; Mackenzie Damron; Kyle B Jones; Dean Weedon; Paul S Carbone; Amanda V Bakian; Deborah A Bilder
Journal:  J Autism Dev Disord       Date:  2016-06

10.  Modeling autism: a systems biology approach.

Authors:  Mary Randolph-Gips; Pramila Srinivasan
Journal:  J Clin Bioinforma       Date:  2012-10-08
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