Literature DB >> 22828997

Neurovascular uncoupling under mild hypoxic hypoxia: an EEG-fMRI study in rats.

Akira Sumiyoshi1, Hideaki Suzuki, Hiroaki Shimokawa, Ryuta Kawashima.   

Abstract

The effects of oxygen availability on neurovascular coupling were investigated using simultaneous electroencephalography (EEG) and functional magnetic resonance imaging (fMRI), in addition to the monitoring of physiological parameters, in 16 α-chloralose-anesthetized rats. Mild hypoxic hypoxia (oxygen saturation=83.6±12.1%) induced significant reductions in fMRI responses (P<0.05) to electrical stimulation in the forepaw, but EEG responses remained unchanged. In addition, the changes in oxygen saturation were linearly correlated with the changes in the fMRI responses. These data further emphasize the importance of oxygen availability, which may regulate neurovascular coupling via the oxygen-dependent enzymatic synthesis of messenger molecules.

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Year:  2012        PMID： 22828997      PMCID： PMC3463877          DOI： 10.1038/jcbfm.2012.111

Source DB:  PubMed          Journal:  J Cereb Blood Flow Metab        ISSN： 0271-678X            Impact factor:   6.200


  25 in total

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2.  A mini-cap for simultaneous EEG and fMRI recording in rodents.

Authors:  Akira Sumiyoshi; Jorge J Riera; Takeshi Ogawa; Ryuta Kawashima
Journal:  Neuroimage       Date:  2010-10-30       Impact factor: 6.556

3.  Oxygen modulation of neurovascular coupling in the retina.

Authors:  Anusha Mishra; Arif Hamid; Eric A Newman
Journal:  Proc Natl Acad Sci U S A       Date:  2011-10-17       Impact factor: 11.205

4.  Coupling between gamma oscillation and fMRI signal in the rat somatosensory cortex: its dependence on systemic physiological parameters.

Authors:  Akira Sumiyoshi; Hideaki Suzuki; Takeshi Ogawa; Jorge J Riera; Hiroaki Shimokawa; Ryuta Kawashima
Journal:  Neuroimage       Date:  2012-01-08       Impact factor: 6.556

5.  Two-photon high-resolution measurement of partial pressure of oxygen in cerebral vasculature and tissue.

Authors:  Sava Sakadzić; Emmanuel Roussakis; Mohammad A Yaseen; Emiri T Mandeville; Vivek J Srinivasan; Ken Arai; Svetlana Ruvinskaya; Anna Devor; Eng H Lo; Sergei A Vinogradov; David A Boas
Journal:  Nat Methods       Date:  2010-08-08       Impact factor: 28.547

6.  Longitudinal MRI studies in the isoflurane-anesthetized rat: long-term effects of a short hypoxic episode on regulation of cerebral blood flow as assessed by pulsed arterial spin labelling.

Authors:  Susanne Wegener; Eric C Wong
Journal:  NMR Biomed       Date:  2008-08       Impact factor: 4.044

7.  Coupling between somatosensory evoked potentials and hemodynamic response in the rat.

Authors:  Maria Angela Franceschini; Ilkka Nissilä; Weicheng Wu; Solomon G Diamond; Giorgio Bonmassar; David A Boas
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Authors:  Grant R J Gordon; Hyun B Choi; Ravi L Rungta; Graham C R Ellis-Davies; Brian A MacVicar
Journal:  Nature       Date:  2008-10-29       Impact factor: 49.962

9.  Neurovascular coupling in rat brain operates independent of hemoglobin deoxygenation.

Authors:  Ute Lindauer; Christoph Leithner; Heike Kaasch; Benjamin Rohrer; Marco Foddis; Martina Füchtemeier; Nikolas Offenhauser; Jens Steinbrink; Georg Royl; Matthias Kohl-Bareis; Ulrich Dirnagl
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Review 10.  Glial and neuronal control of brain blood flow.

Authors:  David Attwell; Alastair M Buchan; Serge Charpak; Martin Lauritzen; Brian A Macvicar; Eric A Newman
Journal:  Nature       Date:  2010-11-11       Impact factor: 49.962
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  9 in total

1.  Noninvasive high-speed photoacoustic tomography of cerebral hemodynamics in awake-moving rats.

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2.  Association between tissue hypoxia, perfusion restrictions, and microvascular architecture alterations with lesion-induced impairment of neurovascular coupling.

Authors:  Andreas Stadlbauer; Thomas M Kinfe; Max Zimmermann; Ilker Eyüpoglu; Nadja Brandner; Michael Buchfelder; Moritz Zaiss; Arnd Dörfler; Sebastian Brandner
Journal:  J Cereb Blood Flow Metab       Date:  2020-08-12       Impact factor: 6.200

3.  Reversal of neurovascular coupling in the default mode network: Evidence from hypoxia.

Authors:  Gabriella Mk Rossetti; Giovanni d'Avossa; Matthew Rogan; Jamie H Macdonald; Samuel J Oliver; Paul G Mullins
Journal:  J Cereb Blood Flow Metab       Date:  2020-06-14       Impact factor: 6.200

4.  Effects of acute mild hypoxia on cerebral blood flow in pilots.

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Journal:  Neurol Sci       Date:  2020-07-11       Impact factor: 3.307

5.  Alteration of spontaneous brain activity in COPD patients.

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Journal:  Int J Chron Obstruct Pulmon Dis       Date:  2016-07-28

6.  Altered amplitude of low-frequency fluctuation in basal ganglia correlates to pulmonary ventilation function in COPD patients: A resting-state fMRI study.

Authors:  Chun-Qiang Lu; Weiwei Xu; Chu-Hui Zeng; Lu-Yao Ge; Yuan-Cheng Wang; Xiang-Pan Meng; Qian Yu; Di Wu; Shenghong Ju
Journal:  Brain Behav       Date:  2019-05-29       Impact factor: 2.708

7.  Effects of mild hypoxia on oxygen extraction fraction responses to brain stimulation.

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Journal:  J Cereb Blood Flow Metab       Date:  2021-02-09       Impact factor: 6.200

Review 8.  The power of using functional fMRI on small rodents to study brain pharmacology and disease.

Authors:  Elisabeth Jonckers; Disha Shah; Julie Hamaide; Marleen Verhoye; Annemie Van der Linden
Journal:  Front Pharmacol       Date:  2015-10-21       Impact factor: 5.810

9.  Neuronal and astrocytic interactions modulate brain endothelial properties during metabolic stresses of in vitro cerebral ischemia.

Authors:  Ganta Vijay Chaitanya; Alireza Minagar; Jonathan S Alexander
Journal:  Cell Commun Signal       Date:  2014-01-17       Impact factor: 5.712
  9 in total

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