Literature DB >> 22826485

Benznidazole shortage makes chagas disease a neglected tropical disease in developed countries: data from Spain.

Miriam Navarro1, Francesca F Norman, José Antonio Pérez-Molina, Rogelio López-Vélez.   

Abstract

Chagas disease is a neglected tropical disease endemic in Latin America. The first-line treatment option is benznidazole, but stocks are expected to run out in the coming months. Spain would need around 5 million benznidazole tablets. This drug shortage could make Chagas disease a neglected tropical disease also in developed countries.

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Year:  2012        PMID： 22826485      PMCID： PMC3435352          DOI： 10.4269/ajtmh.2012.12-0080

Source DB:  PubMed          Journal:  Am J Trop Med Hyg        ISSN： 0002-9637            Impact factor:   2.345


  10 in total

1.  The impact of anti-infective drug shortages on hospitals in the United States: trends and causes.

Authors:  Milena M Griffith; Alan E Gross; Sarah H Sutton; Maureen K Bolon; John S Esterly; Jean A Patel; Michael J Postelnick; Teresa R Zembower; Marc H Scheetz
Journal:  Clin Infect Dis       Date:  2012-01-19       Impact factor: 9.079

2.  Targeted screening and health education for Chagas disease tailored to at-risk migrants in Spain, 2007 to 2010.

Authors:  M Navarro; A Perez-Ayala; A Guionnet; J A Perez-Molina; B Navaza; L Estevez; F Norman; M Flores-Chavez; R Lopez-Velez
Journal:  Euro Surveill       Date:  2011-09-22

3.  Surveillance of Chagas disease in pregnant women in Madrid, Spain, from 2008 to 2010.

Authors:  M D Flores-Chavez; F J Merino; S Garcia-Bujalance; P Martin-Rabadan; P Merino; I Garcia-Bermejo; A Delgado; J Cuadros
Journal:  Euro Surveill       Date:  2011-09-22

4.  Prevalence and vertical transmission of Trypanosoma cruzi infection among pregnant Latin American women attending 2 maternity clinics in Barcelona, Spain.

Authors:  José Muñoz; Oriol Coll; Teresa Juncosa; Mireia Vergés; Marta del Pino; Victoria Fumado; Jordi Bosch; Elizabeth J Posada; Sara Hernandez; Roser Fisa; Josep Maria Boguña; Montserrat Gállego; Sergi Sanz; Montserrat Portús; Joaquim Gascón
Journal:  Clin Infect Dis       Date:  2009-06-15       Impact factor: 9.079

5.  Rationale and design of a randomized placebo-controlled trial assessing the effects of etiologic treatment in Chagas' cardiomyopathy: the BENznidazole Evaluation For Interrupting Trypanosomiasis (BENEFIT).

Authors:  Jose Antonio Marin-Neto; Anis Rassi; Carlos A Morillo; Alvaro Avezum; Stuart J Connolly; Sergio Sosa-Estani; Fernando Rosas; Salim Yusuf
Journal:  Am Heart J       Date:  2008-07       Impact factor: 4.749

6.  Treatment with benznidazole during the chronic phase of experimental Chagas' disease decreases cardiac alterations.

Authors:  Simone Garcia; Carolina O Ramos; Juliana F V Senra; Fabio Vilas-Boas; Maurício M Rodrigues; Antonio C Campos-de-Carvalho; Ricardo Ribeiro-Dos-Santos; Milena B P Soares
Journal:  Antimicrob Agents Chemother       Date:  2005-04       Impact factor: 5.191

Review 7.  Evaluation and treatment of chagas disease in the United States: a systematic review.

Authors:  Caryn Bern; Susan P Montgomery; Barbara L Herwaldt; Anis Rassi; Jose Antonio Marin-Neto; Roberto O Dantas; James H Maguire; Harry Acquatella; Carlos Morillo; Louis V Kirchhoff; Robert H Gilman; Pedro A Reyes; Roberto Salvatella; Anne C Moore
Journal:  JAMA       Date:  2007-11-14       Impact factor: 56.272

8.  Seroprevalence of Trypanosoma cruzi infection in at-risk blood donors in Catalonia (Spain).

Authors:  Maria Piron; Mireia Vergés; José Muñoz; Natàlia Casamitjana; Sergi Sanz; Rosa María Maymó; José Manuel Hernández; Lluís Puig; Montserrat Portús; Joaquim Gascón; Sílvia Sauleda
Journal:  Transfusion       Date:  2008-06-02       Impact factor: 3.157

9.  [Prevalence of american trypanosomiasis in pregnant women from a health area of Valencia, Spain: 2005-2007].

Authors:  Rafael Manuel Ortí Lucas; María Cristina Parada Barba
Journal:  Rev Esp Salud Publica       Date:  2009 Jul-Aug

10.  [Epidemiological surveillance of vertically-transmitted Chagas disease at three maternity hospitals in the Valencian Community].

Authors:  José María Paricio-Talayero; María José Benlloch-Muncharaz; José Ignacio Collar-del-Castillo; Amparo Rubio-Soriano; Concepción Serrat-Pérez; Josefa Magraner-Egea; Leonardo Landa-Rivera; Marta Sánchez-Palomares; Beatriz Beseler-Soto; Luis Santos-Serrano; Manuel Ferriol-Camacho; José Mut-Buigues; Miguel Tomás-Vila; María del Carmen Alonso-Jiménez; Victoria Domínguez-Márquez; Rafael Igual-Adell
Journal:  Enferm Infecc Microbiol Clin       Date:  2008-12       Impact factor: 1.731
  10 in total
  8 in total

1.  Using hospital discharge database to characterize Chagas disease evolution in Spain: there is a need for a systematic approach towards disease detection and control.

Authors:  Zaida Herrador; Eva Rivas; Alin Gherasim; Diana Gomez-Barroso; Jezabel García; Agustín Benito; Pilar Aparicio
Journal:  PLoS Negl Trop Dis       Date:  2015-04-17

2.  Usefulness of real time PCR to quantify parasite load in serum samples from chronic Chagas disease patients.

Authors:  Myllena F Melo; Otacilio C Moreira; Priscila Tenório; Virginia Lorena; Izaura Lorena-Rezende; Wilson Oliveira Júnior; Yara Gomes; Constança Britto
Journal:  Parasit Vectors       Date:  2015-03-12       Impact factor: 3.876

3.  Pharmacokinetic and pharmacodynamic responses in adult patients with Chagas disease treated with a new formulation of benznidazole.

Authors:  Marisa Liliana Fernández; Maria Elena Marson; Juan Carlos Ramirez; Guido Mastrantonio; Alejandro Gabriel Schijman; Jaime Altcheh; Adelina Rosa Riarte; Facundo García Bournissen
Journal:  Mem Inst Oswaldo Cruz       Date:  2016-03-15       Impact factor: 2.743

4.  Spontaneous dormancy protects Trypanosoma cruzi during extended drug exposure.

Authors:  Fernando J Sánchez-Valdéz; Angel Padilla; Wei Wang; Dylan Orr; Rick L Tarleton
Journal:  Elife       Date:  2018-03-26       Impact factor: 8.140

5.  Chagas Disease Treatment and Rational Drug Discovery: A Challenge That Remains.

Authors:  Ana Catarina Cristovão Silva; Maria Carolina Accioly Brelaz-de-Castro; Ana Cristina Lima Leite; Valéria Rêgo Alves Pereira; Marcelo Zaldini Hernandes
Journal:  Front Pharmacol       Date:  2019-08-02       Impact factor: 5.810

6.  High variation in immune responses and parasite phenotypes in naturally acquired Trypanosoma cruzi infection in a captive non-human primate breeding colony in Texas, USA.

Authors:  Angel M Padilla; Phil Y Yao; Tre J Landry; Gretchen M Cooley; Susan M Mahaney; Isabela Ribeiro; John L VandeBerg; Rick L Tarleton
Journal:  PLoS Negl Trop Dis       Date:  2021-03-31

7.  Chagas disease in Spain: need for further public health measures.

Authors:  Miriam Navarro; Bárbara Navaza; Anne Guionnet; Rogelio López-Vélez
Journal:  PLoS Negl Trop Dis       Date:  2012-12-27

8.  Tolerance to nifurtimox and benznidazole in adult patients with chronic Chagas' disease.

Authors:  Yves Jackson; Baptiste Wyssa; François Chappuis
Journal:  J Antimicrob Chemother       Date:  2020-03-01       Impact factor: 5.790
  8 in total

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