Adrian Taruttis1, Vasilis Ntziachristos. 1. Institute for Biological and Medical Imaging, Helmholtz Zentrum München, Ingolstädter Landstrasse 1, 85764 Neuherberg, Germany.
Abstract
OBJECTIVE: Optical imaging is experiencing significant technologic advances. Simultaneously, an array of specific optical imaging agents has brought new capabilities to biomedical research and is edging toward clinical use. We review progress in the translation of macroscopic optical imaging-including fluorescence-guided surgery and endoscopy, intravascular fluorescence imaging, diffuse fluorescence and optical tomography, and multispectral optoacoustics (photoacoustics)-for applications ranging from tumor resection and assessment of atherosclerotic plaques to dermatologic and breast examinations. CONCLUSION: Optical imaging could play a major role in the move from imaging of structure and morphology to the visualization of the individual biologic processes underlying disease and could, therefore, contribute to more accurate diagnostics and improved treatment efficacy.
OBJECTIVE: Optical imaging is experiencing significant technologic advances. Simultaneously, an array of specific optical imaging agents has brought new capabilities to biomedical research and is edging toward clinical use. We review progress in the translation of macroscopic optical imaging-including fluorescence-guided surgery and endoscopy, intravascular fluorescence imaging, diffuse fluorescence and optical tomography, and multispectral optoacoustics (photoacoustics)-for applications ranging from tumor resection and assessment of atherosclerotic plaques to dermatologic and breast examinations. CONCLUSION: Optical imaging could play a major role in the move from imaging of structure and morphology to the visualization of the individual biologic processes underlying disease and could, therefore, contribute to more accurate diagnostics and improved treatment efficacy.
Authors: Eben L Rosenthal; Jason M Warram; Esther de Boer; Thomas K Chung; Melissa L Korb; Margie Brandwein-Gensler; Theresa V Strong; Cecelia E Schmalbach; Anthony B Morlandt; Garima Agarwal; Yolanda E Hartman; William R Carroll; Joshua S Richman; Lisa K Clemons; Lisle M Nabell; Kurt R Zinn Journal: Clin Cancer Res Date: 2015-04-22 Impact factor: 12.531
Authors: Karen Haney; Pushpa Tandon; Rao Divi; Miguel R Ossandon; Houston Baker; Paul C Pearlman Journal: IEEE J Transl Eng Health Med Date: 2017-11-23 Impact factor: 3.316
Authors: B-W Xie; D Park; E R Van Beek; V Blankevoort; Y Orabi; I Que; E L Kaijzel; A Chan; P J Hogg; C W G M Löwik Journal: Cell Death Dis Date: 2013-01-24 Impact factor: 8.469