Literature DB >> 22824812

Are omega-3 fatty acids antidepressants or just mood-improving agents? The effect depends upon diagnosis, supplement preparation, and severity of depression.

P-Y Lin, D Mischoulon, M P Freeman, Y Matsuoka, J Hibbeln, R H Belmaker, K-P Su.   

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Year:  2012        PMID: 22824812      PMCID: PMC3504139          DOI: 10.1038/mp.2012.111

Source DB:  PubMed          Journal:  Mol Psychiatry        ISSN: 1359-4184            Impact factor:   15.992


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  8 in total

1.  A meta-analytic review of polyunsaturated fatty acid compositions in patients with depression.

Authors:  Pao-Yen Lin; Shih-Yi Huang; Kuan-Pin Su
Journal:  Biol Psychiatry       Date:  2010-05-10       Impact factor: 13.382

2.  Meta-analysis of the effects of eicosapentaenoic acid (EPA) in clinical trials in depression.

Authors:  M Elizabeth Sublette; Steven P Ellis; Amy L Geant; J John Mann
Journal:  J Clin Psychiatry       Date:  2011-09-06       Impact factor: 4.384

Review 3.  Omega-3 fatty acids: evidence basis for treatment and future research in psychiatry.

Authors:  Marlene P Freeman; Joseph R Hibbeln; Katherine L Wisner; John M Davis; David Mischoulon; Malcolm Peet; Paul E Keck; Lauren B Marangell; Alexandra J Richardson; James Lake; Andrew L Stoll
Journal:  J Clin Psychiatry       Date:  2006-12       Impact factor: 4.384

4.  Complementary and alternative medicine for major depressive disorder: a meta-analysis of patient characteristics, placebo-response rates, and treatment outcomes relative to standard antidepressants.

Authors:  Marlene P Freeman; David Mischoulon; Enrico Tedeschini; Tracie Goodness; Lee S Cohen; Maurizio Fava; George I Papakostas
Journal:  J Clin Psychiatry       Date:  2010-06       Impact factor: 4.384

Review 5.  Updated systematic review and meta-analysis of the effects of n-3 long-chain polyunsaturated fatty acids on depressed mood.

Authors:  Katherine M Appleton; Peter J Rogers; Andrew R Ness
Journal:  Am J Clin Nutr       Date:  2010-02-03       Impact factor: 7.045

6.  No effect of n-3 long-chain polyunsaturated fatty acid (EPA and DHA) supplementation on depressed mood and cognitive function: a randomised controlled trial.

Authors:  Peter J Rogers; Katherine M Appleton; David Kessler; Tim J Peters; David Gunnell; Robert C Hayward; Susan V Heatherley; Leonie M Christian; Sarah A McNaughton; Andy R Ness
Journal:  Br J Nutr       Date:  2007-10-24       Impact factor: 3.718

7.  Effects of ethyl-eicosapentaenoic acid omega-3 fatty acid supplementation on hot flashes and quality of life among middle-aged women: a double-blind, placebo-controlled, randomized clinical trial.

Authors:  Michel Lucas; Geneviève Asselin; Chantal Mérette; Marie-Josée Poulin; Sylvie Dodin
Journal:  Menopause       Date:  2009 Mar-Apr       Impact factor: 2.953

8.  A meta-analytic review of double-blind, placebo-controlled trials of antidepressant efficacy of omega-3 fatty acids.

Authors:  Pao-Yen Lin; Kuan-Pin Su
Journal:  J Clin Psychiatry       Date:  2007-07       Impact factor: 4.384

  8 in total
  48 in total

1.  Low unesterified:esterified eicosapentaenoic acid (EPA) plasma concentration ratio is associated with bipolar disorder episodes, and omega-3 plasma concentrations are altered by treatment.

Authors:  Erika Fh Saunders; Aubrey Reider; Gagan Singh; Alan J Gelenberg; Stanley I Rapoport
Journal:  Bipolar Disord       Date:  2015-10-01       Impact factor: 6.744

Review 2.  Omega-3 fatty acids for depression in adults.

Authors:  Katherine M Appleton; Hannah M Sallis; Rachel Perry; Andrew R Ness; Rachel Churchill
Journal:  Cochrane Database Syst Rev       Date:  2015-11-05

3.  ω-3 fatty acid intakes are inversely related to elevated depressive symptoms among United States women.

Authors:  May A Beydoun; Marie T Fanelli Kuczmarski; Hind A Beydoun; Joseph R Hibbeln; Michele K Evans; Alan B Zonderman
Journal:  J Nutr       Date:  2013-09-04       Impact factor: 4.798

Review 4.  Focus on fatty acids in the neurometabolic pathophysiology of psychiatric disorders.

Authors:  R J T Mocking; J Assies; H G Ruhé; A H Schene
Journal:  J Inherit Metab Dis       Date:  2018-03-09       Impact factor: 4.982

5.  Clinical implications of eicosapentaenoic acid/arachidonic acid ratio (EPA/AA) in adult patients with congenital heart disease.

Authors:  Miki Kanoh; Kei Inai; Tokuko Shinohara; Hirofumi Tomimatsu; Toshio Nakanishi
Journal:  Heart Vessels       Date:  2017-07-05       Impact factor: 2.037

6.  Suicide mortality in relation to dietary intake of n-3 and n-6 polyunsaturated fatty acids and fish: equivocal findings from 3 large US cohort studies.

Authors:  Alexander C Tsai; Michel Lucas; Olivia I Okereke; Eilis J O'Reilly; Fariba Mirzaei; Ichiro Kawachi; Alberto Ascherio; Walter C Willett
Journal:  Am J Epidemiol       Date:  2014-05-08       Impact factor: 4.897

Review 7.  Pathways of polyunsaturated fatty acid utilization: implications for brain function in neuropsychiatric health and disease.

Authors:  Joanne J Liu; Pnina Green; J John Mann; Stanley I Rapoport; M Elizabeth Sublette
Journal:  Brain Res       Date:  2014-12-08       Impact factor: 3.252

8.  Current evidence for the clinical use of long-chain polyunsaturated n-3 fatty acids to prevent age-related cognitive decline and Alzheimer's disease.

Authors:  P A Dacks; D W Shineman; H M Fillit
Journal:  J Nutr Health Aging       Date:  2013-03       Impact factor: 4.075

9.  Low plasma eicosapentaenoic acid levels are associated with elevated trait aggression and impulsivity in major depressive disorder with a history of comorbid substance use disorder.

Authors:  Anne Mette Beier; Lotte Lauritzen; Hanga C Galfalvy; Thomas B Cooper; Maria A Oquendo; Michael F Grunebaum; J John Mann; M Elizabeth Sublette
Journal:  J Psychiatr Res       Date:  2014-06-26       Impact factor: 4.791

10.  Omega-3 polyunsaturated fatty acid supplementation and white matter changes in major depression.

Authors:  Binod Thapa Chhetry; Adrienne Hezghia; Jeffrey M Miller; Seonjoo Lee; Harry Rubin-Falcone; Thomas B Cooper; Maria A Oquendo; J John Mann; M Elizabeth Sublette
Journal:  J Psychiatr Res       Date:  2016-01-11       Impact factor: 4.791

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