Literature DB >> 22824650

[Neovascular membrane and pregnancy. Treatment with bevacizumab].

I Gómez Ledesma1, M Á de Santiago Rodríguez, I Follana Neira, F León Garrigosa.   

Abstract

CLINICAL CASE: Female in her sixth month of pregnancy, with a history of refractive surgery, who consulted due to a metamorphopsia and decrease in visual acuity in the right eye. A presumed ocular histoplasmosis syndrome (POHS) and a subfoveal choroidal neovascular membrane were observed in the fundoscopy. Two monthly doses of intravitreal bevacizumab were given after the labour, but the third dose was never inyected as the patient became pregnant again. She subsequently had a spontaneous miscarriage. DISCUSSION: Treatment with intravitreal bevacizumab during pregnancy is controversial as it may increase the risk of miscarriage during the first trimester.
Copyright © 2011 Sociedad Española de Oftalmología. Published by Elsevier Espana. All rights reserved.

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Year:  2012        PMID: 22824650     DOI: 10.1016/j.oftal.2011.09.011

Source DB:  PubMed          Journal:  Arch Soc Esp Oftalmol        ISSN: 0365-6691


  2 in total

1.  Dexamethasone intravitreal implant for diabetic macular edema in a pregnant patient.

Authors:  Romi Yoo; Hyung Chan Kim; Hyewon Chung
Journal:  Int J Ophthalmol       Date:  2016-10-18       Impact factor: 1.779

2.  Teratogenic Effects of Intravitreal Injection of Bevacizumab in a Pregnant Rat Model.

Authors:  Shahram Bamdad; Mina Bamdad; Mahsa Khanlari; Yahya Daneshbod; Behzad Khademi
Journal:  Iran J Pharm Res       Date:  2017       Impact factor: 1.696

  2 in total

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