Jong Ha Hwang1. 1. Department of Obstetrics and Gynecology, Dongwon Women's Hospital, 439 Illsan-ro, Ilsandong-gu, Goyang-Si, Gyeonggi-do, 410-829, Republic of Korea. jh36640@hanmail.net
Abstract
OBJECTIVE: A meta-analysis was done to assess the risk of intraoperative and postoperative urologic complications, and laparoscopic radical hysterectomy (LRH) and lymph node dissection. METHODS: Pubmed, EMBASE and Cochrane library were searched for studies published to December, 2011, supplemented by manual searches of relevant bibliographies from the retrieved articles. Two researchers independently extracted the data. Eligible studies had reported perioperative complications and a sample size of at least 10 patients. RESULTS: The search yielded 19 retrospective studies and one prospective cohort study (intraoperative urologic complication, 18 studies; postoperative urologic complication, 16 studies). When all studies were pooled, the odds ratio (OR) of LRH for the risk of intraoperative urologic complications compared to abdominal radical hysterectomy (ARH) was 1.97 [95% confidence interval (CI) 1.23-3.13] and the OR of LRH for postoperative complication risk compared to ARH was 1.35 [95% CI 0.84-2.16]. In subgroup analysis, obesity and laparoscopic type (laparoscopic assisted vaginal radical hysterectomy) were associated with intraoperative urologic complications. CONCLUSION: Laparoscopic radical hysterectomy is associated with a significant increased risk of intraoperative urologic complications.
OBJECTIVE: A meta-analysis was done to assess the risk of intraoperative and postoperative urologic complications, and laparoscopic radical hysterectomy (LRH) and lymph node dissection. METHODS: Pubmed, EMBASE and Cochrane library were searched for studies published to December, 2011, supplemented by manual searches of relevant bibliographies from the retrieved articles. Two researchers independently extracted the data. Eligible studies had reported perioperative complications and a sample size of at least 10 patients. RESULTS: The search yielded 19 retrospective studies and one prospective cohort study (intraoperative urologic complication, 18 studies; postoperative urologic complication, 16 studies). When all studies were pooled, the odds ratio (OR) of LRH for the risk of intraoperative urologic complications compared to abdominal radical hysterectomy (ARH) was 1.97 [95% confidence interval (CI) 1.23-3.13] and the OR of LRH for postoperative complication risk compared to ARH was 1.35 [95% CI 0.84-2.16]. In subgroup analysis, obesity and laparoscopic type (laparoscopic assisted vaginal radical hysterectomy) were associated with intraoperative urologic complications. CONCLUSION: Laparoscopic radical hysterectomy is associated with a significant increased risk of intraoperative urologic complications.
Authors: Cui Hu; Yu Xu; Qianwen Zhang; Qing Liu; Yi Du; Ya Jia; Yue-Dong He; Ai Zheng; Hui Xu; Shuang-Shuang Cui; Yong Tian; Lin Ran; Fengmei Ke Journal: BMJ Open Date: 2022-07-29 Impact factor: 3.006