Literature DB >> 22824476

The genetic epidemiology of nonalcoholic fatty liver disease: toward a personalized medicine.

Silvia Sookoian1, Carlos J Pirola.   

Abstract

The understanding of the genetic bases of complex diseases such as nonalcoholic fatty liver disease opens new opportunities and challenges. This article explores new tools designed toward moving genomic data into clinical medicine, providing putative answers to more practical questions.
Copyright © 2012 Elsevier Inc. All rights reserved.

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Year:  2012        PMID： 22824476     DOI： 10.1016/j.cld.2012.05.011

Source DB:  PubMed          Journal:  Clin Liver Dis        ISSN： 1089-3261            Impact factor:   6.126


  18 in total

1.  Metabolic profiling reveals that PNPLA3 induces widespread effects on metabolism beyond triacylglycerol remodeling in Huh-7 hepatoma cells.

Authors:  Hae-Ki Min; Silvia Sookoian; Carlos J Pirola; Jianfeng Cheng; Faridoddin Mirshahi; Arun J Sanyal
Journal:  Am J Physiol Gastrointest Liver Physiol       Date:  2014-04-24       Impact factor: 4.052

Review 2.  Clinical differences between alcoholic liver disease and nonalcoholic fatty liver disease.

Authors:  Nobuyuki Toshikuni; Mikihiro Tsutsumi; Tomiyasu Arisawa
Journal:  World J Gastroenterol       Date:  2014-07-14       Impact factor: 5.742

3.  An integrative systems genetic analysis of mammalian lipid metabolism.

Authors:  Benjamin L Parker; Anna C Calkin; Marcus M Seldin; Michael F Keating; Elizabeth J Tarling; Pengyi Yang; Sarah C Moody; Yingying Liu; Eser J Zerenturk; Elise J Needham; Matthew L Miller; Bethan L Clifford; Pauline Morand; Matthew J Watt; Ruth C R Meex; Kang-Yu Peng; Richard Lee; Kaushala Jayawardana; Calvin Pan; Natalie A Mellett; Jacquelyn M Weir; Ross Lazarus; Aldons J Lusis; Peter J Meikle; David E James; Thomas Q de Aguiar Vallim; Brian G Drew
Journal:  Nature       Date:  2019-02-27       Impact factor: 49.962

4.  Cell-free DNA methylation as liquid biopsy for the assessment of fibrosis in patients with nonalcoholic steatohepatitis: a gap between innovation and implementation.

Authors:  Silvia Sookoian; Carlos J Pirola
Journal:  Hepatobiliary Surg Nutr       Date:  2017-04       Impact factor: 7.293

Review 5.  Relationships among alcoholic liver disease, antioxidants, and antioxidant enzymes.

Authors:  Kyu-Ho Han; Naoto Hashimoto; Michihiro Fukushima
Journal:  World J Gastroenterol       Date:  2016-01-07       Impact factor: 5.742

Review 6.  Liver enzymes, metabolomics and genome-wide association studies: from systems biology to the personalized medicine.

Authors:  Silvia Sookoian; Carlos J Pirola
Journal:  World J Gastroenterol       Date:  2015-01-21       Impact factor: 5.742

7.  Transcriptional networks implicated in human nonalcoholic fatty liver disease.

Authors:  Hua Ye; Wei Liu
Journal:  Mol Genet Genomics       Date:  2015-04-08       Impact factor: 3.291

8.  PNPLA3, the triacylglycerol synthesis/hydrolysis/storage dilemma, and nonalcoholic fatty liver disease.

Authors:  Silvia Sookoian; Carlos J Pirola
Journal:  World J Gastroenterol       Date:  2012-11-14       Impact factor: 5.742

Review 9.  Role of liver biopsy in nonalcoholic fatty liver disease.

Authors:  I L Ke Nalbantoglu; Elizabeth M Brunt
Journal:  World J Gastroenterol       Date:  2014-07-21       Impact factor: 5.742

10.  Impact of circulating miR-122 for histological features and hepatocellular carcinoma of nonalcoholic fatty liver disease in Japan.

Authors:  Norio Akuta; Yusuke Kawamura; Fumitaka Suzuki; Satoshi Saitoh; Yasuji Arase; Hideo Kunimoto; Yushi Sorin; Shunichiro Fujiyama; Hitomi Sezaki; Tetsuya Hosaka; Masahiro Kobayashi; Yoshiyuki Suzuki; Mariko Kobayashi; Kenji Ikeda; Hiromitsu Kumada
Journal:  Hepatol Int       Date:  2016-04-13       Impact factor: 6.047
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