Literature DB >> 2282218

A comparison of the reduction in the K+ activity of the scala media produced by furosemide and ouabain.

A Shugyo1, N Mori, T Matsunaga.   

Abstract

The endocochlear potential (EP) and the K+ activity in the scala media of the guinea pig were recorded by means of K(+)-sensitive, double-barrelled microelectrodes in the second turn of the cochlea. EP and K+ change were recorded during the perilymphatic perfusion of furosemide and ouabain. Furosemide produced less of a decrease than ouabain in the K+ activity relative to the EP decrease. These results suggest that furosemide reduces the EP via different mechanisms from the inhibition of the K+ secretion potential.

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Year:  1990        PMID： 2282218     DOI： 10.1007/bf00240224

Source DB:  PubMed          Journal:  Eur Arch Otorhinolaryngol        ISSN： 0937-4477            Impact factor:   2.503


  6 in total

1.  Cation transport and cochlear function.

Authors:  W Kuijpers
Journal:  Acta Otolaryngol       Date:  1969 Feb-Mar       Impact factor: 1.494

2.  Effect of ouabain on cochlear potentials and endolymph composition in guinea pigs.

Authors:  T Konishi; M Mendelsohn
Journal:  Acta Otolaryngol       Date:  1970-03       Impact factor: 1.494

3.  Ion transport in guinea pig cochlea. I. Potassium and sodium transport.

Authors:  T Konishi; P E Hamrick; P J Walsh
Journal:  Acta Otolaryngol       Date:  1978 Jul-Aug       Impact factor: 1.494

4.  [DC resting potential in the stria vascularis of the guinea pig cochlea. Changes of the intracellular positive DC potential in the strial cells under various conditions].

Authors:  S Ohyama
Journal:  Nihon Jibiinkoka Gakkai Kaiho       Date:  1982-12-20

5.  Effect of ethacrynic acid, furosemide, and ouabain upon the endolymphatic potential and upon high energy phosphates of the stria vascularis.

Authors:  J Kusakari; I Ise; T H Comegys; I Thalmann; R Thalmann
Journal:  Laryngoscope       Date:  1978-01       Impact factor: 3.325

6.  Permeability to potassium of the endolymph-perilymph barrier and its possible relation to hair cell function.

Authors:  T Konishi; A N Salt
Journal:  Exp Brain Res       Date:  1980       Impact factor: 1.972
  6 in total
  5 in total

1.  Conservation of hearing by simultaneous mutation of Na,K-ATPase and NKCC1.

Authors:  Rodney C Diaz; Ana Elena Vazquez; Hongwei Dou; Dongguang Wei; Emma Lou Cardell; Jerry Lingrel; Gary E Shull; Karen Jo Doyle; Ebenezer N Yamoah
Journal:  J Assoc Res Otolaryngol       Date:  2007-08-04

2.  The mechanism underlying maintenance of the endocochlear potential by the K+ transport system in fibrocytes of the inner ear.

Authors:  Naoko Adachi; Takamasa Yoshida; Fumiaki Nin; Genki Ogata; Soichiro Yamaguchi; Toshihiro Suzuki; Sizuo Komune; Yasuo Hisa; Hiroshi Hibino; Yoshihisa Kurachi
Journal:  J Physiol       Date:  2013-07-08       Impact factor: 5.182

3.  Age-related changes in Na, K-ATPase expression, subunit isoform selection and assembly in the stria vascularis lateral wall of mouse cochlea.

Authors:  Bo Ding; Joseph P Walton; Xiaoxia Zhu; Robert D Frisina
Journal:  Hear Res       Date:  2018-07-10       Impact factor: 3.672

4.  Ouabain Does Not Induce Selective Spiral Ganglion Cell Degeneration in Guinea Pigs.

Authors:  Timo Schomann; Dyan Ramekers; John C M J de Groot; Carola H van der Ploeg; Ferry G J Hendriksen; Stefan Böhringer; Sjaak F L Klis; Johan H M Frijns; Margriet A Huisman
Journal:  Biomed Res Int       Date:  2018-07-31       Impact factor: 3.411

Review 5.  The unique electrical properties in an extracellular fluid of the mammalian cochlea; their functional roles, homeostatic processes, and pathological significance.

Authors:  Fumiaki Nin; Takamasa Yoshida; Seishiro Sawamura; Genki Ogata; Takeru Ota; Taiga Higuchi; Shingo Murakami; Katsumi Doi; Yoshihisa Kurachi; Hiroshi Hibino
Journal:  Pflugers Arch       Date:  2016-08-27       Impact factor: 3.657
  5 in total

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