Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Neuroprotection of apelin and its signaling pathway.

Literature DB >> 22820556

Neuroprotection of apelin and its signaling pathway.

Baohua Cheng¹, Jing Chen, Bo Bai, Qing Xin.

Abstract

Apelin was initially isolated from bovine stomach and is an endogenous neuropeptide. It is a native ligand of the apelin receptor (APJ). Some research has found that apelin peptides alter blood pressure, feeding behavior, and pituitary hormone release. However, a new neuroprotective effect of apelin peptides was only recently discovered. This review summarizes the evidence of apelin-neuroprotection, which has the potential to cure acute and chronic neurological diseases.

Entities: Disease Gene Species

Mesh：

Substances：

Year: 2012 PMID： 22820556 DOI： 10.1016/j.peptides.2012.07.012

Source DB: PubMed Journal: Peptides ISSN： 0196-9781 Impact factor: 3.750

Keyword Cloud
Cited

21 in total

Review 1. Adipose tissue and vascular inflammation in coronary artery disease.

Authors: Enrica Golia; Giuseppe Limongelli; Francesco Natale; Fabio Fimiani; Valeria Maddaloni; Pina Elvira Russo; Lucia Riegler; Renatomaria Bianchi; Mario Crisci; Gaetano Di Palma; Paolo Golino; Maria Giovanna Russo; Raffaele Calabrò; Paolo Calabrò
Journal: World J Cardiol Date: 2014-07-26

2. VEGF-B selectively regenerates injured peripheral neurons and restores sensory and trophic functions.

Authors: Victor H Guaiquil; Zan Pan; Natalia Karagianni; Shima Fukuoka; Gemstonn Alegre; Mark I Rosenblatt
Journal: Proc Natl Acad Sci U S A Date: 2014-11-17 Impact factor: 11.205

3. The Concise Guide to PHARMACOLOGY 2013/14: G protein-coupled receptors.

Authors: Stephen P H Alexander; Helen E Benson; Elena Faccenda; Adam J Pawson; Joanna L Sharman; Michael Spedding; John A Peters; Anthony J Harmar
Journal: Br J Pharmacol Date: 2013-12 Impact factor: 8.739

4. Apelin-13 Protects PC12 Cells from Corticosterone-Induced Apoptosis Through PI3K and ERKs Activation.

Authors: Yunjun Zou; Bo Wang; Wan Fu; Shouhong Zhou; Yaxiong Nie; Shaowen Tian
Journal: Neurochem Res Date: 2016-03-09 Impact factor: 3.996

5. Apelin-36 Protects HT22 Cells Against Oxygen-Glucose Deprivation/Reperfusion-Induced Oxidative Stress and Mitochondrial Dysfunction by Promoting SIRT1-Mediated PINK1/Parkin-Dependent Mitophagy.

Authors: Ziqi Shao; Shanshan Dou; Junge Zhu; Huiqing Wang; Dandan Xu; Chunmei Wang; Baohua Cheng; Bo Bai
Journal: Neurotox Res Date: 2021-02-13 Impact factor: 3.911

6. Modulation of pain in pediatric sickle cell disease: understanding the balance between endothelin mediated vasoconstriction and apelin mediated vasodilation.

Authors: Terika P Smith; Alyssa M Schlenz; Jeffrey C Schatz; Rangan Maitra; Sarah M Sweitzer
Journal: Blood Cells Mol Dis Date: 2014-11-26 Impact factor: 3.039

Neuroprotection of apelin and its signaling pathway.

Review 1. Adipose tissue and vascular inflammation in coronary artery disease.

2. VEGF-B selectively regenerates injured peripheral neurons and restores sensory and trophic functions.

3. The Concise Guide to PHARMACOLOGY 2013/14: G protein-coupled receptors.

4. Apelin-13 Protects PC12 Cells from Corticosterone-Induced Apoptosis Through PI3K and ERKs Activation.

5. Apelin-36 Protects HT22 Cells Against Oxygen-Glucose Deprivation/Reperfusion-Induced Oxidative Stress and Mitochondrial Dysfunction by Promoting SIRT1-Mediated PINK1/Parkin-Dependent Mitophagy.

6. Modulation of pain in pediatric sickle cell disease: understanding the balance between endothelin mediated vasoconstriction and apelin mediated vasodilation.

7. Discovery of a novel small molecule agonist scaffold for the APJ receptor.

8. Intranasal Delivery of Apelin-13 Is Neuroprotective and Promotes Angiogenesis After Ischemic Stroke in Mice.

9. Lateral intracerebroventricular injection of Apelin-13 inhibits apoptosis after cerebral ischemia/reperfusion injury.

Review 10. Physical Exercise-Induced Myokines in Neurodegenerative Diseases.