Literature DB >> 22815333

Clinical, radiological and functional assessment of pulmonary status in patients with achalasia cardia before and after treatment.

Rajinder Parshad1, Sudheer Kumar Devana, Karthik Panchanatheeswaran, Anoop Saraya, Govind K Makharia, Surendra Kumar Sharma, Ashu Seith Bhalla.   

Abstract

OBJECTIVES: Patients with achalasia have respiratory symptoms due to chronic microaspiration. Achalasia can lead to radiological and functional changes in the lung. We studied the effect of either balloon dilatation or laparoscopic Heller's cardiomyotomy on the reversal of these changes in the lung.
METHODS: Thirty patients with achalasia were included in this study. Oesophageal symptoms and pulmonary symptoms were recorded. Pulmonary function tests (PFTs) were done at baseline and at the end of 6 months. High-resolution computed tomography of the chest was performed prior to treatment and repeated 6 months after treatment if found abnormal at the initial evaluation.
RESULTS: The mean age of the patients was 30.97 years and mean duration of symptoms was 22.5 months. Fifteen patients (50%) had respiratory symptoms, nocturnal cough being the commonest symptom in 13 (43.3%). Thirteen patients (43.3%) had parenchymal lung changes on high-resolution computed tomography (HRCT). Eight patients (28.5%) had functional abnormalities in the lungs in the form of restrictive airway disease. Nineteen patients opted for Laparoscopic Heller's cardiomyotomy, while 11 patients underwent pneumatic dilatation. Six months after treatment, the respiratory symptoms resolved in all except two patients (13.3%). Four patients (66.6%) with active lung changes at HRCT showed resolution at 6 months. There was improvement in functional parameters on PFT evaluation with normalization of PFT in one patient.
CONCLUSIONS: Pulmonary symptoms as well as radiological and functional abnormalities are common in patients with achalasia. Treatment in the form of pneumatic dilatation or Lap cardiomyotomy improves pulmonary symptoms.

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Year:  2012        PMID: 22815333     DOI: 10.1093/ejcts/ezs421

Source DB:  PubMed          Journal:  Eur J Cardiothorac Surg        ISSN: 1010-7940            Impact factor:   4.191


  7 in total

1.  Respiratory dysfunction is common in patients with achalasia and improves after pneumatic dilation.

Authors:  Mahesh Gupta; Uday C Ghoshal; Shikha Jindal; Asha Misra; Alok Nath; Vivek A Saraswat
Journal:  Dig Dis Sci       Date:  2013-12-20       Impact factor: 3.199

2.  Anesthesia in per-oral endoscopic myotomy: A large tertiary care centre experience.

Authors:  Santosh Darisetty; Zaheer Nabi; Mohan Ramchandani; Radhika Chavan; Rama Kotla; D Nageshwar Reddy
Journal:  Indian J Gastroenterol       Date:  2017-08-24

3.  Hospitalization for esophageal achalasia in the United States.

Authors:  Daniela Molena; Benedetto Mungo; Miloslawa Stem; Anne O Lidor
Journal:  World J Gastrointest Endosc       Date:  2015-09-25

4.  Outcomes of esophagectomy for esophageal achalasia in the United States.

Authors:  Daniela Molena; Benedetto Mungo; Miloslawa Stem; Richard L Feinberg; Anne O Lidor
Journal:  J Gastrointest Surg       Date:  2013-08-21       Impact factor: 3.452

5.  Gastrointestinal Dysmotility and the Implications for Respiratory Disease.

Authors:  Lusine Ambartsumyan; Samuel Nurko; Rachel Rosen
Journal:  Curr Treat Options Pediatr       Date:  2019-04-26

6.  A case of chronic cough caused by achalasia misconceived as gastroesophageal reflux disease.

Authors:  Hea Yoon Kwon; Jun Hyeok Lim; Yong Woon Shin; Cheol-Woo Kim
Journal:  Allergy Asthma Immunol Res       Date:  2014-04-04       Impact factor: 5.764

7.  Esophageal achalasia: An unusual reason for lung abscess.

Authors:  Seiji Shiota; Ryoko Kuribayashi; Rie Utsunomiya; Eishi Miyazaki
Journal:  J Gen Fam Med       Date:  2022-01-14
  7 in total

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