Literature DB >> 22814458

Targeting both rs12979860 and rs8099917 polymorphisms with a single-tube high-resolution melting assay for IL28b genotyping.

Kok Siong Poon1, Sherry Sze Yee Ho, Julian Wei-Tze Tang, Cui Wen Chua, Lily Chiu, Evelyn Siew-Chuan Koay.   

Abstract

A rapid, duplex, high-resolution melting interleukin-28B gene (IL28B) genotyping assay, targeting both rs12979860 and rs8099917 polymorphisms, was developed and validated using 30 DNA samples from healthy volunteers. A linkage study on 300 healthy Singaporeans showed variable haplotypes. When the assay was applied to plasma DNA from 50 hepatitis C virus genotype-1 (HCV-1)-infected patients, five compound heterozygous types were detected.

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Year:  2012        PMID： 22814458      PMCID： PMC3457426          DOI： 10.1128/JCM.01718-12

Source DB:  PubMed          Journal:  J Clin Microbiol        ISSN： 0095-1137            Impact factor:   5.948


  11 in total

1.  Impact of IL28B genotype on the early and sustained virologic response in treatment-naïve patients with chronic hepatitis C.

Authors:  Albert Friedrich Stättermayer; Rudolf Stauber; Harald Hofer; Karoline Rutter; Sandra Beinhardt; Thomas Matthias Scherzer; Kerstin Zinober; Christian Datz; Andreas Maieron; Emina Dulic-Lakovic; Harald H Kessler; Petra Steindl-Munda; Michael Strasser; Christoph Krall; Peter Ferenci
Journal:  Clin Gastroenterol Hepatol       Date:  2010-08-20       Impact factor: 11.382

2.  Amino acid substitution in hepatitis C virus core region and genetic variation near the interleukin 28B gene predict viral response to telaprevir with peginterferon and ribavirin.

Authors:  Norio Akuta; Fumitaka Suzuki; Miharu Hirakawa; Yusuke Kawamura; Hiromi Yatsuji; Hitomi Sezaki; Yoshiyuki Suzuki; Tetsuya Hosaka; Masahiro Kobayashi; Mariko Kobayashi; Satoshi Saitoh; Yasuji Arase; Kenji Ikeda; Kazuaki Chayama; Yusuke Nakamura; Hiromitsu Kumada
Journal:  Hepatology       Date:  2010-08       Impact factor: 17.425

3.  Interleukin-28B genotyping by melt-mismatch amplification mutation assay PCR analysis using single nucleotide polymorphisms rs12979860 and rs8099917, a useful tool for prediction of therapy response in hepatitis C patients.

Authors:  Salvador Fonseca-Coronado; Gilberto Vaughan; Mayra Yolanda Cruz-Rivera; Juan Carlos Carpio-Pedroza; Karina Ruiz-Tovar; Juan Alberto Ruiz-Pacheco; Alejandro Escobar-Gutiérrez
Journal:  J Clin Microbiol       Date:  2011-05-25       Impact factor: 5.948

Review 4.  IL28B genetic polymorphism testing in the era of direct acting antivirals therapy for chronic hepatitis C: ten years too late?

Authors:  Donald M Jensen; Stanislas Pol
Journal:  Liver Int       Date:  2012-02       Impact factor: 5.828

Review 5.  The IL-28 genotype: how it will affect the care of patients with hepatitis C virus infection.

Authors:  Brian L Pearlman
Journal:  Curr Gastroenterol Rep       Date:  2011-02

6.  The rs8099917 polymorphism, when determined by a suitable genotyping method, is a better predictor for response to pegylated alpha interferon/ribavirin therapy in Japanese patients than other single nucleotide polymorphisms associated with interleukin-28B.

Authors:  Kiyoaki Ito; Katsuya Higami; Naohiko Masaki; Masaya Sugiyama; Motokazu Mukaide; Hiroaki Saito; Yoshihiko Aoki; Yo Sato; Masatoshi Imamura; Kazumoto Murata; Hideyuki Nomura; Shuhei Hige; Hiroshi Adachi; Keisuke Hino; Hiroshi Yatsuhashi; Etsuro Orito; Satomi Kani; Yasuhito Tanaka; Masashi Mizokami
Journal:  J Clin Microbiol       Date:  2011-03-09       Impact factor: 5.948

7.  Genetic variation in IL28B predicts hepatitis C treatment-induced viral clearance.

Authors:  Dongliang Ge; Jacques Fellay; Alexander J Thompson; Jason S Simon; Kevin V Shianna; Thomas J Urban; Erin L Heinzen; Ping Qiu; Arthur H Bertelsen; Andrew J Muir; Mark Sulkowski; John G McHutchison; David B Goldstein
Journal:  Nature       Date:  2009-08-16       Impact factor: 49.962

8.  An update on treatment of genotype 1 chronic hepatitis C virus infection: 2011 practice guideline by the American Association for the Study of Liver Diseases.

Authors:  Marc G Ghany; David R Nelson; Doris B Strader; David L Thomas; Leonard B Seeff
Journal:  Hepatology       Date:  2011-09-26       Impact factor: 17.425

9.  Cubic exact solutions for the estimation of pairwise haplotype frequencies: implications for linkage disequilibrium analyses and a web tool 'CubeX'.

Authors:  Tom R Gaunt; Santiago Rodríguez; Ian Nm Day
Journal:  BMC Bioinformatics       Date:  2007-11-02       Impact factor: 3.169

10.  Hardy-Weinberg equilibrium testing of biological ascertainment for Mendelian randomization studies.

Authors:  Santiago Rodriguez; Tom R Gaunt; Ian N M Day
Journal:  Am J Epidemiol       Date:  2009-01-06       Impact factor: 4.897
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  1 in total

1.  Real world experience with pegylated interferon and ribavirin in hepatitis C genotype 1 population with favourable IL28B polymorphism.

Authors:  Victoria Ekstrom; Rajneesh Kumar; Yi Zhao; Mei Ling Yee; Cynthia Sung; Dorothy Toh; Poh Yen Loh; Jessica Tan; Eng Kiong Teo; Wan Cheng Chow
Journal:  Gastroenterol Rep (Oxf)       Date:  2016-10-24
  1 in total

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