Literature DB >> 22813923

Is preterm delivery indicated in fetuses with gastroschisis and antenatally detected bowel dilation?

Megan S Wilson1, Mary A Carroll, Stephane A Braun, William F Walsh, John B Pietsch, Kelly A Bennett.   

Abstract

INTRODUCTION: Due to the controversy surrounding diagnostic ultrasound evaluations and elective preterm delivery of fetuses with gastroschisis, we sought to calculate the predictive value of bowel dilation in fetuses with gastroschisis and evaluate the effect of preterm delivery on neonatal outcomes.
MATERIALS AND METHODS: Ultrasounds and medical records of 103 mother-infant pairs with fetal gastroschisis were reviewed. Eighty-nine pairs met the criteria. Intestinal complications, gestational age at delivery, birth weight, and number of abdominal surgeries were documented.
RESULTS: Forty-eight fetuses (54%) had bowel dilation and 41 (46%) did not. The positive predictive value of bowel dilation for complicated gastroschisis was 21%. There were 50 (56%) preterm and 39 (44%) term deliveries. The mean birth weight was 2,114 g (SD = 507) and 2,659 g (SD = 687), p = 0.001. For infants delivered preterm, the mean number of postnatal abdominal surgeries was 2.1 (SD = 1.1) as compared to 1.3 (SD = 0.5) surgical procedures for those infants delivered at term gestation. This was not statistically significant. With respect to hospital stay for each group, the mean length of neonatal intensive care unit admission was 48 days (SD = 33) in the preterm group and 35 days (SD = 50) in the term group, which was not statistically significant. DISCUSSION: Ultrasound-detected bowel dilation was not predictive of important intestinal complications. Our data did not substantiate any benefit for elective preterm delivery of neonates with gastroschisis.
Copyright © 2012 S. Karger AG, Basel.

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Year:  2012        PMID: 22813923     DOI: 10.1159/000338925

Source DB:  PubMed          Journal:  Fetal Diagn Ther        ISSN: 1015-3837            Impact factor:   2.587


  4 in total

1.  Outcomes in infants with prenatally diagnosed gastroschisis and planned preterm delivery.

Authors:  Carmen Mesas Burgos; Anna Svenningsson; Jenny Hammarqvist Vejde; Tina Granholm; Peter Conner
Journal:  Pediatr Surg Int       Date:  2015-09-23       Impact factor: 1.827

2.  The influence of gestational age, mode of delivery and abdominal wall closure method on the surgical outcome of neonates with uncomplicated gastroschisis.

Authors:  Maria V Fraga; Pablo Laje; William H Peranteau; Holly L Hedrick; Nahla Khalek; Juliana S Gebb; Julie S Moldenhauer; Mark P Johnson; Alan W Flake; N Scott Adzick
Journal:  Pediatr Surg Int       Date:  2018-02-07       Impact factor: 1.827

3.  Gut inflammation and expression of ICC in a fetal lamb model of fetoscopic intervention for gastroschisis.

Authors:  Thomas Krebs; Michael Boettcher; Hansjörg Schäfer; Georg Eschenburg; Katharina Wenke; Birgit Appl; Beate Roth; Thomas Andreas; Carla Schmitz; Rebecca Fahje; Birthe Jacobsen; Bastian Tiemann; Konrad Reinshagen; Kurt Hecher; Robert Bergholz
Journal:  Surg Endosc       Date:  2014-03-20       Impact factor: 4.584

Review 4.  Gastroschisis: antenatal sonographic predictors of adverse neonatal outcome.

Authors:  Rachael Page; Zachary Michael Ferraro; Felipe Moretti; Karen Fung Kee Fung
Journal:  J Pregnancy       Date:  2014-12-22
  4 in total

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