Literature DB >> 22810454

On the prevention and analysis of missing data in randomized clinical trials: the state of the art.

Daniel O Scharfstein1, Joseph Hogan, Amir Herman.   

Abstract

We summarize and elaborate on the recently published National Research Council report entitled "The Prevention and Treatment of Missing Data in Clinical Trials." We tailor our discussion to orthopaedic trials. In particular, we discuss the intent-to-treat principle, review study design and prevention ideas to minimize missing data, and present state-of-the-art sensitivity analysis methods for analyzing and reporting the results of studies with missing data.

Mesh：

Year:  2012        PMID： 22810454      PMCID： PMC3393113          DOI： 10.2106/JBJS.L.00273

Source DB:  PubMed          Journal:  J Bone Joint Surg Am        ISSN： 0021-9355            Impact factor:   5.284


  4 in total

1.  Nonoperative treatment compared with plate fixation of displaced midshaft clavicular fractures. A multicenter, randomized clinical trial.

Authors: 
Journal:  J Bone Joint Surg Am       Date:  2007-01       Impact factor: 5.284

2.  Bias reduction with an adjustment for participants' intent to dropout of a randomized controlled clinical trial.

Authors:  Andrew C Leon; Hakan Demirtas; Donald Hedeker
Journal:  Clin Trials       Date:  2007       Impact factor: 2.486

3.  Intention-to-treat analysis and accounting for missing data in orthopaedic randomized clinical trials.

Authors:  Amir Herman; Itamar Busheri Botser; Shay Tenenbaum; Ahron Chechick
Journal:  J Bone Joint Surg Am       Date:  2009-09       Impact factor: 5.284

4.  Efficacy and safety of balloon kyphoplasty compared with non-surgical care for vertebral compression fracture (FREE): a randomised controlled trial.

Authors:  Douglas Wardlaw; Steven R Cummings; Jan Van Meirhaeghe; Leonard Bastian; John B Tillman; Jonas Ranstam; Richard Eastell; Peter Shabe; Karen Talmadge; Steven Boonen
Journal:  Lancet       Date:  2009-02-24       Impact factor: 79.321
  4 in total
  10 in total

1.  To attend, or not to attend: Examining caregiver intentions and study compliance in a pediatric, randomized controlled trial.

Authors:  Jacqueline A Sullivan; Anna M Wiese; Kelly M Boone; Joseph Rausch; Sarah A Keim
Journal:  Clin Trials       Date:  2020-01-27       Impact factor: 2.486

Review 2.  Cochrane in CORR®: surgery for rotator cuff disease (review).

Authors:  Moin Khan; Nicole Simunovic; Matthew Provencher
Journal:  Clin Orthop Relat Res       Date:  2014-08-15       Impact factor: 4.176

3.  Challenges in outcome measurement: clinical research perspective.

Authors:  Daniel P O'Connor; Mark R Brinker
Journal:  Clin Orthop Relat Res       Date:  2013-11       Impact factor: 4.176

4.  The (in)stability of 21st century orthopedic patient contact information and its implications on clinical research: A cross-sectional study.

Authors:  Daniel A London; Jeffrey G Stepan; Charles A Goldfarb; Martin I Boyer; Ryan P Calfee
Journal:  Clin Trials       Date:  2016-11-30       Impact factor: 2.486

Review 5.  OARSI Clinical Trials Recommendations: Key analytic considerations in design, analysis, and reporting of randomized controlled trials in osteoarthritis.

Authors:  E Losina; J Ranstam; J E Collins; T J Schnitzer; J N Katz
Journal:  Osteoarthritis Cartilage       Date:  2015-05       Impact factor: 6.576

Review 6.  Statistical issues and methods in designing and analyzing survival studies.

Authors:  Muditha Perera; Alok Kumar Dwivedi
Journal:  Cancer Rep (Hoboken)       Date:  2019-05-09

7.  The prevention and handling of the missing data.

Authors:  Hyun Kang
Journal:  Korean J Anesthesiol       Date:  2013-05-24

8.  Methylprednisolone for the Treatment of Patients with Acute Spinal Cord Injuries: A Propensity Score-Matched Cohort Study from a Canadian Multi-Center Spinal Cord Injury Registry.

Authors:  Nathan Evaniew; Vanessa K Noonan; Nader Fallah; Brian K Kwon; Carly S Rivers; Henry Ahn; Christopher S Bailey; Sean D Christie; Daryl R Fourney; R John Hurlbert; A G Linassi; Michael G Fehlings; Marcel F Dvorak
Journal:  J Neurotrauma       Date:  2015-07-17       Impact factor: 5.269

Review 9.  Strategies for dealing with missing data in clinical trials: from design to analysis.

Authors:  James D Dziura; Lori A Post; Qing Zhao; Zhixuan Fu; Peter Peduzzi
Journal:  Yale J Biol Med       Date:  2013-09-20

10.  Empty polyetheretherketone (PEEK) cages in anterior cervical diskectomy and fusion (ACDF) show slow radiographic fusion that reduces clinical improvement: results from the prospective multicenter "PIERCE-PEEK" study.

Authors:  Olaf Suess; Martin Schomaker; Mario Cabraja; Marco Danne; Theodoros Kombos; Michael Hanna
Journal:  Patient Saf Surg       Date:  2017-04-28
  10 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.