Literature DB >> 22809894

Symptoms of depression and PTSD are associated with elevated alcohol demand.

James G Murphy1, Ali M Yurasek, Ashley A Dennhardt, Jessica R Skidmore, Meghan E McDevitt-Murphy, James MacKillop, Matthew P Martens.   

Abstract

BACKGROUND: Behavioral economic demand curves measure individual differences in motivation for alcohol and have been associated with problematic patterns of alcohol use, but little is known about the variables that may contribute to elevated demand. Negative visceral states have been theorized to increase demand for alcohol and to contribute to excessive drinking patterns, but little empirical research has evaluated this possibility. The present study tested the hypothesis that symptoms of depression and PTSD would be uniquely associated with elevated alcohol demand even after taking into account differences in typical drinking levels.
METHOD: An Alcohol Purchase Task (APT) was used to generate a demand curve measure of alcohol reinforcement in a sample of 133 college students (50.4% male, 64.4% Caucasian, 29.5% African-American) who reported at least one heavy drinking episode (5/4 or more drinks in one occasion for a man/woman) in the past month. Participants also completed standard measures of alcohol consumption and symptoms of depression and PTSD.
RESULTS: Regression analyses indicated that symptoms of depression were associated with higher demand intensity (alcohol consumption when price=0; ΔR(2)=.05, p=.002) and lower elasticity (ΔR(2)=.04, p=.03), and that PTSD symptoms were associated with all five demand curve metrics (ΔR(2)=.04-.07, ps<.05).
CONCLUSIONS: These findings provide support for behavioral economic models of addiction that highlight the role of aversive visceral states in increasing the reward value of alcohol and provide an additional theoretical model to explain the association between negative affect and problematic drinking patterns.
Copyright © 2012 Elsevier Ireland Ltd. All rights reserved.

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Year:  2012        PMID: 22809894      PMCID: PMC3775331          DOI: 10.1016/j.drugalcdep.2012.06.022

Source DB:  PubMed          Journal:  Drug Alcohol Depend        ISSN: 0376-8716            Impact factor:   4.492


  59 in total

1.  Modeling drug consumption in the clinic using simulation procedures: demand for heroin and cigarettes in opioid-dependent outpatients.

Authors:  E A Jacobs; W K Bickel
Journal:  Exp Clin Psychopharmacol       Date:  1999-11       Impact factor: 3.157

2.  Replacing relative reinforcing efficacy with behavioral economic demand curves.

Authors:  Matthew W Johnson; Warren K Bickel
Journal:  J Exp Anal Behav       Date:  2006-01       Impact factor: 2.468

3.  Relative reinforcing efficacy of alcohol among college student drinkers.

Authors:  James G Murphy; James MacKillop
Journal:  Exp Clin Psychopharmacol       Date:  2006-05       Impact factor: 3.157

4.  Is talk "cheap"? An initial investigation of the equivalence of alcohol purchase task performance for hypothetical and actual rewards.

Authors:  Michael T Amlung; John Acker; Monika K Stojek; James G Murphy; James MacKillop
Journal:  Alcohol Clin Exp Res       Date:  2011-10-21       Impact factor: 3.455

5.  The continuing conundrum of craving.

Authors:  Stephen T Tiffany; Jennifer Wray
Journal:  Addiction       Date:  2009-06-25       Impact factor: 6.526

6.  Associations between depression, distress tolerance, delay discounting, and alcohol-related problems in European American and African American college students.

Authors:  Ashley A Dennhardt; James G Murphy
Journal:  Psychol Addict Behav       Date:  2011-10-10

7.  Psychopathology associated with drinking and alcohol use disorders in the college and general adult populations.

Authors:  Deborah A Dawson; Bridget F Grant; Frederick S Stinson; Patricia S Chou
Journal:  Drug Alcohol Depend       Date:  2005-02-14       Impact factor: 4.492

8.  The effect of drink price and next-day responsibilities on college student drinking: a behavioral economic analysis.

Authors:  Jessica R Skidmore; James G Murphy
Journal:  Psychol Addict Behav       Date:  2011-03

9.  Validating the primary care posttraumatic stress disorder screen and the posttraumatic stress disorder checklist with soldiers returning from combat.

Authors:  Paul D Bliese; Kathleen M Wright; Amy B Adler; Oscar Cabrera; Carl A Castro; Charles W Hoge
Journal:  J Consult Clin Psychol       Date:  2008-04

10.  Longitudinal differences in alcohol use in early adulthood.

Authors:  Philip R Costanzo; Patrick S Malone; Daniel Belsky; Stefan Kertesz; Mark Pletcher; Frank A Sloan
Journal:  J Stud Alcohol Drugs       Date:  2007-09       Impact factor: 2.582

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  37 in total

1.  Validation of a behavioral economic purchase task for assessing drug abuse liability.

Authors:  James MacKillop; Nicholas I Goldenson; Matthew G Kirkpatrick; Adam M Leventhal
Journal:  Addict Biol       Date:  2018-01-05       Impact factor: 4.280

2.  Alcohol Demand, Future Orientation, and Craving Mediate the Relation Between Depressive and Stress Symptoms and Alcohol Problems.

Authors:  Kathryn E Soltis; Meghan E McDevitt-Murphy; James G Murphy
Journal:  Alcohol Clin Exp Res       Date:  2017-05-22       Impact factor: 3.455

Review 3.  Behavioral economic demand assessments in the addictions.

Authors:  Elizabeth R Aston; Rachel N Cassidy
Journal:  Curr Opin Psychol       Date:  2019-01-28

4.  Latent factor structure of a behavioral economic marijuana demand curve.

Authors:  Elizabeth R Aston; Samantha G Farris; James MacKillop; Jane Metrik
Journal:  Psychopharmacology (Berl)       Date:  2017-05-16       Impact factor: 4.530

5.  Depressive Symptoms and Cigarette Demand as a Function of Induced Stress.

Authors:  Jennifer Dahne; James G Murphy; Laura MacPherson
Journal:  Nicotine Tob Res       Date:  2016-05-31       Impact factor: 4.244

6.  Drinking motives mediate the relationship between alcohol reward value and alcohol problems in military veterans.

Authors:  Ashley A Dennhardt; James G Murphy; Meghan E McDevitt-Murphy; Joah L Williams
Journal:  Psychol Addict Behav       Date:  2016-12

7.  PTSD symptom presentation among people with alcohol and drug use disorders: Comparisons by substance of abuse.

Authors:  Emily R Dworkin; Sonya Wanklyn; Paul R Stasiewicz; Scott F Coffey
Journal:  Addict Behav       Date:  2017-08-18       Impact factor: 3.913

8.  Applying behavioral economic theory to problematic Internet use: An initial investigation.

Authors:  Samuel F Acuff; James MacKillop; James G Murphy
Journal:  Psychol Addict Behav       Date:  2018-11

9.  Depressive symptoms as predictors of alcohol problem domains and reinforcement among heavy drinking college students.

Authors:  Samuel F Acuff; Kathryn E Soltis; Matthew T Luciano; Lidia Z Meshesha; Paola Pedrelli; Ashley A Dennhardt; James G Murphy
Journal:  Psychol Addict Behav       Date:  2018-10-04

10.  Reciprocal associations between PTSD symptoms and alcohol involvement in college: a three-year trait-state-error analysis.

Authors:  Jennifer P Read; Jeffrey D Wardell; Craig R Colder
Journal:  J Abnorm Psychol       Date:  2013-11
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