Literature DB >> 22808911

Conformation-specific effects of Raf kinase inhibitors.

Xiaolun Wang1, Joseph Kim.   

Abstract

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Year:  2012        PMID： 22808911     DOI： 10.1021/jm300613w

Source DB:  PubMed          Journal:  J Med Chem        ISSN： 0022-2623            Impact factor:   7.446


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  6 in total

Review 1.  RAS-targeted therapies: is the undruggable drugged?

Authors:  Amanda R Moore; Scott C Rosenberg; Frank McCormick; Shiva Malek
Journal:  Nat Rev Drug Discov       Date:  2020-06-11       Impact factor: 84.694

2.  N-(3-Ethynyl-2,4-difluorophenyl)sulfonamide Derivatives as Selective Raf Inhibitors.

Authors:  Yingjun Li; Huimin Cheng; Zhang Zhang; Xiaoxi Zhuang; Jinfeng Luo; Huoyou Long; Yang Zhou; Yong Xu; Rana Taghipouran; Dan Li; Adam Patterson; Jeff Smaill; Zhengchao Tu; Donghai Wu; Xiaomei Ren; Ke Ding
Journal:  ACS Med Chem Lett       Date:  2015-03-18       Impact factor: 4.345

Review 3.  Regulation of RAF protein kinases in ERK signalling.

Authors:  Hugo Lavoie; Marc Therrien
Journal:  Nat Rev Mol Cell Biol       Date:  2015-05       Impact factor: 94.444

4.  Bisarylureas Based on 1H-Pyrazolo[3,4-d]pyrimidine Scaffold as Novel Pan-RAF Inhibitors with Potent Anti-Proliferative Activities: Structure-Based Design, Synthesis, Biological Evaluation and Molecular Modelling Studies.

Authors:  Yu Fu; Yuanyuan Wang; Shanhe Wan; Zhonghuang Li; Guangfa Wang; Jiajie Zhang; Xiaoyun Wu
Journal:  Molecules       Date:  2017-03-29       Impact factor: 4.411

Review 5.  Exploration of type II binding mode: A privileged approach for kinase inhibitor focused drug discovery?

Authors:  Zheng Zhao; Hong Wu; Li Wang; Yi Liu; Stefan Knapp; Qingsong Liu; Nathanael S Gray
Journal:  ACS Chem Biol       Date:  2014-04-29       Impact factor: 5.100

6.  Phosphorylation of RAF Kinase Dimers Drives Conformational Changes that Facilitate Transactivation.

Authors:  Pablo G Jambrina; Nora Rauch; Ruth Pilkington; Katja Rybakova; Lan K Nguyen; Boris N Kholodenko; Nicolae-Viorel Buchete; Walter Kolch; Edina Rosta
Journal:  Angew Chem Int Ed Engl       Date:  2015-12-08       Impact factor: 15.336
  6 in total

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