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Literature DB >> 22806689

Molecular pathways in pancreatic carcinogenesis.

Anne M Macgregor-Das¹, Christine A Iacobuzio-Donahue.

Abstract

Pancreatic cancer is a genetic disease. Pancreatic cancers develop from one of three precursor lesions, pancreatic intraepithelial neoplasia (PanIN), intraductal papillary mucinous neoplasms (IPMNs), and mucinous cystic neoplasms (MCNs), and each arises in association with distinct genetic alterations. These alterations not only provide insight into the fundamental origins of pancreatic cancer but provide ample opportunity for improving early diagnosis and management of cystic precursors.

Entities: CellLine Chemical Disease Gene Species

Mesh：

Substances：

Year: 2012 PMID： 22806689 PMCID： PMC3661191 DOI： 10.1002/jso.23213

Source DB: PubMed Journal: J Surg Oncol ISSN： 0022-4790 Impact factor: 3.454

62 in total

Review 1. Hyperactive Ras in developmental disorders and cancer.

Authors: Suzanne Schubbert; Kevin Shannon; Gideon Bollag
Journal: Nat Rev Cancer Date: 2007-04 Impact factor: 60.716

2. Frequent mutations of chromatin remodeling gene ARID1A in ovarian clear cell carcinoma.

Authors: Siân Jones; Tian-Li Wang; Ie-Ming Shih; Tsui-Lien Mao; Kentaro Nakayama; Richard Roden; Ruth Glas; Dennis Slamon; Luis A Diaz; Bert Vogelstein; Kenneth W Kinzler; Victor E Velculescu; Nickolas Papadopoulos
Journal: Science Date: 2010-09-08 Impact factor: 47.728

3. BRAF and KRAS gene mutations in intraductal papillary mucinous neoplasm/carcinoma (IPMN/IPMC) of the pancreas.

Authors: Frank Schönleben; Wanglong Qiu; Karl C Bruckman; Nancy T Ciau; Xiaojun Li; Margaret H Lauerman; Harold Frucht; John A Chabot; John D Allendorf; Helen E Remotti; Gloria H Su
Journal: Cancer Lett Date: 2006-11-09 Impact factor: 8.679

Review 4. Regulation of Wnt/beta-catenin signaling by protein kinases.

Authors: Esther M Verheyen; Cara J Gottardi
Journal: Dev Dyn Date: 2010-01 Impact factor: 3.780

5. DPC4 gene status of the primary carcinoma correlates with patterns of failure in patients with pancreatic cancer.

Authors: Christine A Iacobuzio-Donahue; Baojin Fu; Shinichi Yachida; Mingde Luo; Hisashi Abe; Clark M Henderson; Felip Vilardell; Zheng Wang; Jesse W Keller; Priya Banerjee; Joseph M Herman; John L Cameron; Charles J Yeo; Marc K Halushka; James R Eshleman; Marian Raben; Alison P Klein; Ralph H Hruban; Manuel Hidalgo; Daniel Laheru
Journal: J Clin Oncol Date: 2009-03-09 Impact factor: 44.544

Review 6. The management of cystic lesions of the pancreas.

Authors: Peter J Allen; Murray F Brennan
Journal: Adv Surg Date: 2007

Review 7. Pancreatic cysts: pathologic classification, differential diagnosis, and clinical implications.

Authors: Olca Basturk; Ipek Coban; N Volkan Adsay
Journal: Arch Pathol Lab Med Date: 2009-03 Impact factor: 5.534

Review 8. LKB1 and AMPK family signaling: the intimate link between cell polarity and energy metabolism.

Authors: Marnix Jansen; Jean Paul Ten Klooster; G Johan Offerhaus; Hans Clevers
Journal: Physiol Rev Date: 2009-07 Impact factor: 37.312

9. Novel somatic and germline mutations in cancer candidate genes in glioblastoma, melanoma, and pancreatic carcinoma.

Authors: Asha Balakrishnan; Fonnet E Bleeker; Simona Lamba; Monica Rodolfo; Maria Daniotti; Aldo Scarpa; Angela A van Tilborg; Sieger Leenstra; Carlo Zanon; Alberto Bardelli
Journal: Cancer Res Date: 2007-04-15 Impact factor: 12.701

10. The genomic landscapes of human breast and colorectal cancers.

Authors: Laura D Wood; D Williams Parsons; Siân Jones; Jimmy Lin; Tobias Sjöblom; Rebecca J Leary; Dong Shen; Simina M Boca; Thomas Barber; Janine Ptak; Natalie Silliman; Steve Szabo; Zoltan Dezso; Vadim Ustyanksky; Tatiana Nikolskaya; Yuri Nikolsky; Rachel Karchin; Paul A Wilson; Joshua S Kaminker; Zemin Zhang; Randal Croshaw; Joseph Willis; Dawn Dawson; Michail Shipitsin; James K V Willson; Saraswati Sukumar; Kornelia Polyak; Ben Ho Park; Charit L Pethiyagoda; P V Krishna Pant; Dennis G Ballinger; Andrew B Sparks; James Hartigan; Douglas R Smith; Erick Suh; Nickolas Papadopoulos; Phillip Buckhaults; Sanford D Markowitz; Giovanni Parmigiani; Kenneth W Kinzler; Victor E Velculescu; Bert Vogelstein
Journal: Science Date: 2007-10-11 Impact factor: 47.728

29 in total

1. Utilization of ancillary studies in the cytologic diagnosis of biliary and pancreatic lesions: the Papanicolaou Society of Cytopathology guidelines for pancreatobiliary cytology.

Authors: Lester J Layfield; Hormoz Ehya; Armando C Filie; Ralph H Hruban; Nirag Jhala; Loren Joseph; Philippe Vielh; Martha B Pitman
Journal: Diagn Cytopathol Date: 2014-04 Impact factor: 1.582

Review 2. Long non-coding RNAs in cancer invasion and metastasis.

Authors: Xiao-han Shen; Peng Qi; Xiang Du
Journal: Mod Pathol Date: 2014-06-13 Impact factor: 7.842

Review 3. Role of abnormal lipid metabolism in development, progression, diagnosis and therapy of pancreatic cancer.

Authors: Julian Swierczynski; Areta Hebanowska; Tomasz Sledzinski
Journal: World J Gastroenterol Date: 2014-03-07 Impact factor: 5.742

Review 4. Evolution and dynamics of pancreatic cancer progression.

Authors: S Yachida; C A Iacobuzio-Donahue
Journal: Oncogene Date: 2013-02-18 Impact factor: 9.867

5. PR55α Subunit of Protein Phosphatase 2A Supports the Tumorigenic and Metastatic Potential of Pancreatic Cancer Cells by Sustaining Hyperactive Oncogenic Signaling.

Authors: Ashley L Hein; Parthasarathy Seshacharyulu; Satyanarayana Rachagani; Yuri M Sheinin; Michel M Ouellette; Moorthy P Ponnusamy; Marc C Mumby; Surinder K Batra; Ying Yan
Journal: Cancer Res Date: 2016-02-18 Impact factor: 12.701

6. Expression of long non-coding RNA LOC285194 and its prognostic significance in human pancreatic ductal adenocarcinoma.

Authors: Yue-Chao Ding; Wei Yu; Chao Ma; Qian Wang; Chang-Shan Huang; Tao Huang
Journal: Int J Clin Exp Pathol Date: 2014-10-15