Literature DB >> 22805737

Into the wardrobe of Narnia: beyond HIV infection a world of cardiovascular risk.

Marco Colotto1, Alessandra Renzi, Cosimo Durante.   

Abstract

A 38-years-old HIV-hepatitis C virus (HCV) coinfected woman presented to us for dyslipidemia. Clinical, familial and laboratory data were consistent with the diagnosis of familial heterozygous hypercholesterolaemia. History, clinical examination and laboratory findings also supported suspected acromegaly. A pituitary MRI showed a sellar macroadenoma that was removed by transphenoidal surgery without complications. MRI carried out 6 months after surgery showed almost complete removal of the adenoma. This case report describes an uncommon association of diseases, very different for aetiology--genetic for FH, infectious for HIV and HCV, caused by excessive hormone secretion for acromegaly--clinical features and therapy, but all sharing a significant impact on cardiovascular risk as a common feature.

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Year:  2012        PMID: 22805737      PMCID: PMC4542969          DOI: 10.1136/bcr-2012-006230

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  8 in total

Review 1.  Cardiovascular risk and body-fat abnormalities in HIV-infected adults.

Authors:  Steven Grinspoon; Andrew Carr
Journal:  N Engl J Med       Date:  2005-01-06       Impact factor: 91.245

Review 2.  Medical progress: Acromegaly.

Authors:  Shlomo Melmed
Journal:  N Engl J Med       Date:  2006-12-14       Impact factor: 91.245

Review 3.  Cardiovascular manifestations of HIV infection.

Authors:  Jennifer E Ho; Priscilla Y Hsue
Journal:  Heart       Date:  2009-07       Impact factor: 5.994

4.  Hepatitis C virus coinfection and the risk of cardiovascular disease among HIV-infected patients.

Authors:  R Bedimo; A O Westfall; M Mugavero; H Drechsler; N Khanna; M Saag
Journal:  HIV Med       Date:  2010-02-15       Impact factor: 3.180

Review 5.  Acromegaly.

Authors:  Massimo Scacchi; Francesco Cavagnini
Journal:  Pituitary       Date:  2006       Impact factor: 4.107

Review 6.  Guidelines for the diagnosis and management of heterozygous familial hypercholesterolemia.

Authors:  Fernando Civeira
Journal:  Atherosclerosis       Date:  2004-03       Impact factor: 5.162

7.  Hepatitis C virus infection and the risk of coronary disease.

Authors:  Adeel A Butt; Wang Xiaoqiang; Matthew Budoff; David Leaf; Lewis H Kuller; Amy C Justice
Journal:  Clin Infect Dis       Date:  2009-07-15       Impact factor: 9.079

8.  Combination antiretroviral therapy and the risk of myocardial infarction.

Authors:  Nina Friis-Møller; Caroline A Sabin; Rainer Weber; Antonella d'Arminio Monforte; Wafaa M El-Sadr; Peter Reiss; Rodolphe Thiébaut; Linda Morfeldt; Stephane De Wit; Christian Pradier; Gonzalo Calvo; Matthew G Law; Ole Kirk; Andrew N Phillips; Jens D Lundgren
Journal:  N Engl J Med       Date:  2003-11-20       Impact factor: 91.245

  8 in total

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