| Literature DB >> 2280418 |
K K Gambhir1, J Mathews, R Parui, I A Cruz, A O Hosten, M G Dillard.
Abstract
We have studied the percentage of 22Na+ uptake in cell suspensions; 0.4 to 2.0 x 10(9) erythrocytes/mL from diabetic uremic patients with secondary hypertension and from normal subjects. Suspensions from diabetic uremic patients with secondary hypertension 0.42 +/- 0.06 to 2.05 +/- 0.28; normal subjects showed a percentage uptake of 22Na+ of 0.27 +/- 0.05 to 1.28 +/- 0.22. The uptake of 22Na+ in 2.0 x 10(9) cells/mL was 60% more (P less than .05) in diabetic uremic patients than in the controls. These studies indicate that 22Na+ influx determinations may be used to distinguish secondary hypertensive patients from normal subjects.Entities:
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Year: 1990 PMID: 2280418 PMCID: PMC2571561
Source DB: PubMed Journal: J Natl Med Assoc ISSN: 0027-9684 Impact factor: 1.798