Literature DB >> 2280418

Sodium-22 influx into erythrocytes from diabetic hypertensive patients on maintenance hemodialysis.

K K Gambhir1, J Mathews, R Parui, I A Cruz, A O Hosten, M G Dillard.   

Abstract

We have studied the percentage of 22Na+ uptake in cell suspensions; 0.4 to 2.0 x 10(9) erythrocytes/mL from diabetic uremic patients with secondary hypertension and from normal subjects. Suspensions from diabetic uremic patients with secondary hypertension 0.42 +/- 0.06 to 2.05 +/- 0.28; normal subjects showed a percentage uptake of 22Na+ of 0.27 +/- 0.05 to 1.28 +/- 0.22. The uptake of 22Na+ in 2.0 x 10(9) cells/mL was 60% more (P less than .05) in diabetic uremic patients than in the controls. These studies indicate that 22Na+ influx determinations may be used to distinguish secondary hypertensive patients from normal subjects.

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Year:  1990        PMID: 2280418      PMCID: PMC2571561     

Source DB:  PubMed          Journal:  J Natl Med Assoc        ISSN: 0027-9684            Impact factor:   1.798


  9 in total

1.  AN ION TRANSPORT DEFECT IN ERYTHROCYTES FROM UREMIC PATIENTS.

Authors:  L G WELT; J R SACHS; T J MCMANUS
Journal:  Trans Assoc Am Physicians       Date:  1964

2.  Altered sodium permeability, calcium binding and Na-K-ATPase activity in the red blood cell membrane in essential hypertension.

Authors:  Y V Postnov; S N Orlov; A Shevchenko; A M Adler
Journal:  Pflugers Arch       Date:  1977-11-23       Impact factor: 3.657

3.  Increased erythrocyte permeability to Li and Na in the spontaneously hypertensive rat.

Authors:  S M Friedman; M Nakashima; R A McIndoe; C L Friedman
Journal:  Experientia       Date:  1976-04-15

4.  Insulin radioreceptor assay for human erythrocytes.

Authors:  K K Gambhir; J A Archer; L Carter
Journal:  Clin Chem       Date:  1977-09       Impact factor: 8.327

5.  23Na nuclear magnetic resonance study of Na+-K+ pump inhibition by a fraction from uremic toxins.

Authors:  P Gallice; J P Monti; M Baz; A Murisasco; A Crevat
Journal:  Clin Chem       Date:  1988-10       Impact factor: 8.327

6.  Sodium transport by red blood cells in uremia.

Authors:  M F Villamil; V Rettori; C R Kleeman
Journal:  J Lab Clin Med       Date:  1968-08

7.  Assessment of red cell sodium transport in essential hypertension.

Authors:  J R Mahoney; N L Etkin; J D McSwigan; J W Eaton
Journal:  Blood       Date:  1982-02       Impact factor: 22.113

8.  Functional and metabolic studies on red blood cell sodium transport in chronic uremia.

Authors:  H J Kramer; D Gospodinov; F Krück
Journal:  Nephron       Date:  1976       Impact factor: 2.847

9.  A simpler procedure to study sodium-22 uptake (ouabain insensitive) in human erythrocytes.

Authors:  K K Gambhir; R Parui; S G Nerurkar; N Dave; J Mathews; P P Mehrotra; C L Curry
Journal:  Clin Biochem       Date:  1988-06       Impact factor: 3.281

  9 in total

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