Literature DB >> 22803513

Cross-talk between FGF and other cytokine signalling pathways during endochondral bone development.

Min Jin1, Xiaolan Du, Lin Chen.   

Abstract

FGF (fibroblast growth factor)/FGFR (FGF receptor) signalling plays an essential role in both endochondral and intramembranous bone development. FGF signalling pathways are important for the earliest stages of limb development and throughout skeletal development. The activity and the outcome of this signalling pathway during bone development are also influenced by many other intracellular and extracellular signals. In this review, we focus on the interplay between FGF signalling and other pathways, which is tightly regulated both spatially and temporally during endochondral skeletal development.

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Year:  2012        PMID： 22803513     DOI： 10.1042/CBI20110352

Source DB:  PubMed          Journal:  Cell Biol Int        ISSN： 1065-6995            Impact factor:   3.612


  6 in total

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  6 in total

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