| Literature DB >> 22803078 |
O P Yatsenko1, A N Silkov, E A Khrapov, M L Filipenko, V A Kozlov, S V Sennikov.
Abstract
The spectrum of alternatively spliced IL-4 and IL-6 gene mRNA was studied in peripheral blood mononuclears from healthy donors and in human fetal tissues. It was found that the expression of alternatively spliced IL-4 and IL-6 gene mRNA in fetal tissues is tissue specific and that hemopoiesis- and immunopoiesis-related tissues differ by the amount of IL-4 and IL-4δ2 mRNA. An mRNA variant IL-4alt3 carrying partial exon 3 deletion was for the first time identified in human mononuclear cells.Entities:
Mesh：
Substances：
Year: 2012 PMID： 22803078 DOI： 10.1007/s10517-012-1520-3
Source DB: PubMed Journal: Bull Exp Biol Med ISSN： 0007-4888 Impact factor: 0.804