Literature DB >> 22802478

Brain metastasis from medullary thyroid carcinoma.

P Börcek1, S L Asa, F Gentili, S Ezzat, T-R Kiehl.   

Abstract

The brain is an exceedingly rare site of metastasis in medullary thyroid carcinoma (MTC). A 50-year-old female who had a history of micro-MTC 11 years prior developed a cerebellar metastasis which was incidentally discovered. Imaging revealed a right cerebellar hemispheric mass with contrast enhancement on CT scans. Histopathologic exam demonstrated a metastatic tumour composed of nodules and sheets of large tumour cells with abundant cytoplasm. Immunohistochemistry confirmed the origin from a MTC. This case report highlights the unique features of an unusual metastatic brain tumour, which followed an indolent course for a long time despite multiple distant metastases.

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Year:  2010        PMID: 22802478      PMCID: PMC3029950          DOI: 10.1136/bcr.09.2010.3301

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  14 in total

1.  Brain metastases from medullary thyroid carcinoma in a patient with multiple endocrine neoplasia type 2A.

Authors:  S U Pitale; E Melian; C Thomas; J F Moley; T Origitano; G W Sizemore
Journal:  Thyroid       Date:  1999-11       Impact factor: 6.568

Review 2.  The management of advanced thyroid cancer.

Authors:  P C Wilson; B M Millar; J D Brierley
Journal:  Clin Oncol (R Coll Radiol)       Date:  2004-12       Impact factor: 4.126

3.  Intracranial metastasis from medullary carcinoma of the thyroid 25 years after primary surgery.

Authors:  S M R Kabir; M S Zafar; H L Brydon
Journal:  Br J Neurosurg       Date:  2006-06       Impact factor: 1.596

Review 4.  Single brain metastasis from thyroid cancer: report of twelve cases and review of the literature.

Authors:  M Salvati; A Frati; G Rocchi; R Masciangelo; A Antonaci; F M Gagliardi; R Delfini
Journal:  J Neurooncol       Date:  2001-01       Impact factor: 4.130

5.  Fatal differentiated thyroid cancer.

Authors:  T Kobayashi; H Asakawa; Y Tamaki; K Umeshita; M Monden
Journal:  J Surg Oncol       Date:  1996-06       Impact factor: 3.454

6.  Management of intracranial metastases of differentiated carcinoma of thyroid.

Authors:  B M Biswal; C S Bal; M S Sandhu; A K Padhy; G K Rath
Journal:  J Neurooncol       Date:  1994       Impact factor: 4.130

7.  Prognosis and treatment of brain metastases in thyroid carcinoma.

Authors:  A C Chiu; E S Delpassand; S I Sherman
Journal:  J Clin Endocrinol Metab       Date:  1997-11       Impact factor: 5.958

8.  [Solitary brain metastasis from medullary carcinoma of the thyroid].

Authors:  Takeshi Mikami; Jun Niwa; Tsukasa Kubota; Masahiko Chiba
Journal:  No Shinkei Geka       Date:  2003-08

9.  Management of brain metastases from thyroid carcinoma: a study of 16 pathologically confirmed cases over 25 years.

Authors:  Robert R McWilliams; Caterina Giannini; Ian D Hay; John L Atkinson; Scott L Stafford; Jan C Buckner
Journal:  Cancer       Date:  2003-07-15       Impact factor: 6.860

10.  Medullary cell carcinoma of the thyroid: metastases to the central nervous system.

Authors:  J Timothy; C Kerawala; L Brazil; J Bartlett; B Doshi
Journal:  Eur J Surg Oncol       Date:  1995-06       Impact factor: 4.424

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  4 in total

Review 1.  Revised American Thyroid Association guidelines for the management of medullary thyroid carcinoma.

Authors:  Samuel A Wells; Sylvia L Asa; Henning Dralle; Rossella Elisei; Douglas B Evans; Robert F Gagel; Nancy Lee; Andreas Machens; Jeffrey F Moley; Furio Pacini; Friedhelm Raue; Karin Frank-Raue; Bruce Robinson; M Sara Rosenthal; Massimo Santoro; Martin Schlumberger; Manisha Shah; Steven G Waguespack
Journal:  Thyroid       Date:  2015-06       Impact factor: 6.568

2.  Response to Selective RET Inhibition With LOXO-292 in a Patient With RET Fusion-Positive Lung Cancer With Leptomeningeal Metastases.

Authors:  Robin Guo; Mark Schreyer; Jason C Chang; S Michael Rothenberg; Dahlia Henry; Paolo Cotzia; Mark G Kris; Natasha Rekhtman; Robert J Young; David M Hyman; Alexander Drilon
Journal:  JCO Precis Oncol       Date:  2019-06-03

Review 3.  Testicular and inguinal lymph node metastases of medullary thyroid cancer: a case report and review of the literature.

Authors:  Marialuisa Appetecchia; Agnese Barnabei; Vincenzo Pompeo; Steno Sentinelli; Roberto Baldelli; Salvatore Maria Corsello; Francesco Torino
Journal:  BMC Endocr Disord       Date:  2014-10-11       Impact factor: 2.763

4.  Unusual gastric mucosal infiltration by a medullary thyroid carcinoma: a case report.

Authors:  T Karrasch; W Doppl; F C Roller; A Schäffler; R Schäffer; S Gattenlöhner
Journal:  J Med Case Rep       Date:  2016-07-27
  4 in total

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