Literature DB >> 22802438

Variation in inflammatory/regulatory cytokines in secondary, tertiary, and quaternary challenges with dengue virus.

Beatriz Sierra1, Ana B Pérez, Mayling Alvarez, Gissel García, Katrin Vogt, Eglys Aguirre, Kathrin Schmolke, Hans-Dieter Volk, María G Guzmán.   

Abstract

Secondary heterologous dengue infection is a risk factor for severe disease manifestations because of the immune-enhancement phenomenon. Succeeding clinical infections are seldom reported, and the clinical course of tertiary and quaternary dengue infections is not clear. Cuba represents a unique environment to study tertiary/quaternary dengue infections in a population with known clinical and serologic dengue markers and no dengue endemicity. We took advantage of this exceptional epidemiologic condition to study the effect of primary, secondary, tertiary, and quaternary dengue infection exposure on the expression of pro-inflammatory and regulatory cytokines, critical in dengue infection pathogenesis, by using a dengue infection ex vivo model. Whereas secondary exposure induced a high cytokine response, we found a significantly lower expression of tumor necrosis factor-α, interferon-γ, interleukin-10, and tumor growth factor-β after tertiary and quaternary infectious challenge. Significant differences in expression of the cytokines were seen between the dengue immune profiles, suggesting that the sequence in which the immune system encounters serotypes may be important in determining the nature of the immune response to subsequent infections.

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Year:  2012        PMID: 22802438      PMCID: PMC3435361          DOI: 10.4269/ajtmh.2012.11-0531

Source DB:  PubMed          Journal:  Am J Trop Med Hyg        ISSN: 0002-9637            Impact factor:   2.345


  74 in total

1.  Influence of the dengue serotype, previous dengue infection, and plasma viral load on clinical presentation and outcome during a dengue-2 and dengue-4 co-epidemic.

Authors:  Laurent Thomas; Olivier Verlaeten; André Cabié; Stéphane Kaidomar; Victor Moravie; Jenny Martial; Fatiha Najioullah; Yves Plumelle; Christiane Fonteau; Philippe Dussart; Raymond Césaire
Journal:  Am J Trop Med Hyg       Date:  2008-06       Impact factor: 2.345

2.  T lymphocyte responses to heterologous secondary dengue virus infections.

Authors:  Alan L Rothman
Journal:  Ann N Y Acad Sci       Date:  2009-09       Impact factor: 5.691

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Journal:  Am J Trop Med Hyg       Date:  1988-01       Impact factor: 2.345

4.  A study of fatal hemorrhagic dengue cases in Cuba, 1981.

Authors:  M G Guzmán; G Kourí; L Morier; M Soler; A Fernández
Journal:  Bull Pan Am Health Organ       Date:  1984

5.  The role of cytokines in activation of coagulation and fibrinolysis in dengue shock syndrome.

Authors:  Catharina Suharti; Eric C M van Gorp; Tatty E Setiati; Wil M V Dolmans; Robert J Djokomoeljanto; C Erik Hack; Cate Hugo ten; Jos W M van der Meer
Journal:  Thromb Haemost       Date:  2002-01       Impact factor: 5.249

6.  Serotype-specific differences in the risk of dengue hemorrhagic fever: an analysis of data collected in Bangkok, Thailand from 1994 to 2006.

Authors:  Jessica R Fried; Robert V Gibbons; Siripen Kalayanarooj; Stephen J Thomas; Anon Srikiatkhachorn; In-Kyu Yoon; Richard G Jarman; Sharone Green; Alan L Rothman; Derek A T Cummings
Journal:  PLoS Negl Trop Dis       Date:  2010-03-02

7.  Partial nucleotide and amino acid sequences of the envelope and the envelope/nonstructural protein-1 gene junction of four dengue-2 virus strains isolated during the 1981 Cuban epidemic.

Authors:  M G Guzman; V Deubel; J L Pelegrino; D Rosario; M Marrero; C Sariol; G Kouri
Journal:  Am J Trop Med Hyg       Date:  1995-03       Impact factor: 2.345

8.  [Dengue hemorrhagic fever serotype and infection pattern in a Colombian endemic area].

Authors:  Raquel E Ocazionez; Sergio Y Gómez; Fabián M Cortés
Journal:  Rev Salud Publica (Bogota)       Date:  2007 Apr-Jun

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Journal:  Southeast Asian J Trop Med Public Health       Date:  1990-12       Impact factor: 0.267

10.  High pro-inflammatory cytokine secretion and loss of high avidity cross-reactive cytotoxic T-cells during the course of secondary dengue virus infection.

Authors:  Tao Dong; Edward Moran; Nguyen Vinh Chau; Cameron Simmons; Kerstin Luhn; Yanchun Peng; Bridget Wills; Nguyen Phuong Dung; Le Thi Thu Thao; Tran Tinh Hien; Andrew McMichael; Jeremy Farrar; Sarah Rowland-Jones
Journal:  PLoS One       Date:  2007-12-05       Impact factor: 3.240

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  6 in total

1.  High-dimensional CyTOF analysis of dengue virus-infected human DCs reveals distinct viral signatures.

Authors:  Rebecca E Hamlin; Adeeb Rahman; Theodore R Pak; Kevin Maringer; Ignacio Mena; Dabeiba Bernal-Rubio; Uma Potla; Ana M Maestre; Anthony C Fredericks; El-Ad D Amir; Andrew Kasarskis; Irene Ramos; Miriam Merad; Ana Fernandez-Sesma
Journal:  JCI Insight       Date:  2017-07-06

Review 2.  Recent advances in understanding dengue.

Authors:  Sophie Yacoub; Juthathip Mongkolsapaya; Gavin Screaton
Journal:  F1000Res       Date:  2016-01-19

3.  IL-10 and socs3 Are Predictive Biomarkers of Dengue Hemorrhagic Fever.

Authors:  Lilian Karem Flores-Mendoza; Tania Estrada-Jiménez; Virginia Sedeño-Monge; Margarita Moreno; María Del Consuelo Manjarrez; Guadalupe González-Ochoa; Lourdes Millán-Pérez Peña; Julio Reyes-Leyva
Journal:  Mediators Inflamm       Date:  2017-07-30       Impact factor: 4.711

4.  Detection of post-vaccination enhanced dengue virus infection in macaques: An improved model for early assessment of dengue vaccines.

Authors:  Maria Beatriz Borges; Renato Sergio Marchevsky; Renata Carvalho Pereira; Ygara da Silva Mendes; Luiz Gustavo Almeida Mendes; Leonardo Diniz-Mendes; Michael A Cruz; Ouafaâ Tahmaoui; Sébastien Baudart; Marcos Freire; Akira Homma; Kirsten Schneider-Ohrum; David W Vaughn; Yannick Vanloubbeeck; Clarisse Lorin; Marie-Pierre Malice; Elena Caride; Lucile Warter
Journal:  PLoS Pathog       Date:  2019-04-22       Impact factor: 6.823

5.  Primary dengue virus infections induce differential cytokine production in Mexican patients.

Authors:  Sergio Isaac de la Cruz Hernández; Henry Nelson Puerta-Guardo; Hilario Flores Aguilar; Silvia González Mateos; Irma López Martinez; Vianney Ortiz-Navarrete; Juan E Ludert; Rosa María del Angel
Journal:  Mem Inst Oswaldo Cruz       Date:  2016-03       Impact factor: 2.743

6.  Transmission-clearance trade-offs indicate that dengue virulence evolution depends on epidemiological context.

Authors:  Rotem Ben-Shachar; Katia Koelle
Journal:  Nat Commun       Date:  2018-06-15       Impact factor: 14.919

  6 in total

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