Literature DB >> 22802325

Iron deficiency in a male with multiple myeloma.

V Singh1, N Bhattarai, M Panda.   

Abstract

A 58-year-old man with long standing unexplained iron deficiency anaemia presented with severe hypercalcaemia and was subsequently diagnosed with multiple myeloma. Anaemia in multiple myeloma is usually normochromic and normocytic.1 To our knowledge, there are no reported cases in the English literature of true iron deficiency associated with multiple myeloma. Our case highlights the importance of pursuing the aetiology of iron deficiency, especially in a middle aged male. It also reinforces the fact that severe hypercalcaemia usually has a malignant aetiology.

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Year:  2010        PMID: 22802325      PMCID: PMC3030095          DOI: 10.1136/bcr.04.2010.2956

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  9 in total

1.  Nonsecretory multiple myeloma.

Authors:  Iman A Abdalla; Imad A Tabbara
Journal:  South Med J       Date:  2002-07       Impact factor: 0.954

Review 2.  Hematopoiesis and cytokines. Relevance to cancer and aging.

Authors:  C A Baraldi-Junkins; A C Beck; G Rothstein
Journal:  Hematol Oncol Clin North Am       Date:  2000-02       Impact factor: 3.722

Review 3.  An approach to iron-deficiency anemia.

Authors:  I Rasul; G P Kandel
Journal:  Can J Gastroenterol       Date:  2001-11       Impact factor: 3.522

4.  Negative regulation of erythroblast maturation by Fas-L(+)/TRAIL(+) highly malignant plasma cells: a major pathogenetic mechanism of anemia in multiple myeloma.

Authors:  Franco Silvestris; Paola Cafforio; Marco Tucci; Franco Dammacco
Journal:  Blood       Date:  2002-02-15       Impact factor: 22.113

Review 5.  The implications of anemia in multiple myeloma.

Authors:  Moshe Mittelman
Journal:  Clin Lymphoma       Date:  2003-08

6.  Evaluation of the gastrointestinal tract in patients with iron-deficiency anemia.

Authors:  D C Rockey; J P Cello
Journal:  N Engl J Med       Date:  1993-12-02       Impact factor: 91.245

7.  Hepcidin, a key regulator of iron metabolism, is transcriptionally activated by p53.

Authors:  Orly Weizer-Stern; Konstantin Adamsky; Ofer Margalit; Osnat Ashur-Fabian; David Givol; Ninette Amariglio; Gideon Rechavi
Journal:  Br J Haematol       Date:  2007-07       Impact factor: 6.998

8.  Involvement of hepcidin in the anemia of multiple myeloma.

Authors:  Sanjai Sharma; Elizabeta Nemeth; Yi-Hsiang Chen; Julia Goodnough; Alissa Huston; G D Roodman; Tomas Ganz; Alan Lichtenstein
Journal:  Clin Cancer Res       Date:  2008-06-01       Impact factor: 12.531

9.  Review of 1027 patients with newly diagnosed multiple myeloma.

Authors:  Robert A Kyle; Morie A Gertz; Thomas E Witzig; John A Lust; Martha Q Lacy; Angela Dispenzieri; Rafael Fonseca; S Vincent Rajkumar; Janice R Offord; Dirk R Larson; Matthew E Plevak; Terry M Therneau; Philip R Greipp
Journal:  Mayo Clin Proc       Date:  2003-01       Impact factor: 7.616

  9 in total

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