Literature DB >> 227993

Characterization of interferon messenger RNA from human lymphoblastoid cells.

J Morser, J Flint, A Meager, H Graves, P N Baker, A Colman, D C Burke.   

Abstract

After treatment with Sendai virus, Namalwa cells form large amounts of interferon. RNA extracted from treated whole cells or from their polysomes was injected into Xenopus laevis oocytes and the interferon formed was titrated. The results show that the amount of interferon mRNA was maximal by 9 h after treatment of the cells with Sendai virus and then declined. Sucrose gradient centrifugation of the mRNA gave substantial purification and showed that its size was 12 S.

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Year:  1979        PMID: 227993     DOI: 10.1099/0022-1317-44-1-231

Source DB:  PubMed          Journal:  J Gen Virol        ISSN: 0022-1317            Impact factor:   3.891


  4 in total

1.  Heterogeneity of interferon mRNA species from Sendai virus-induced human lymphoblastoid (Namalva) cells and Newcastle disease virus-induced murine fibroblastoid (L) cells.

Authors:  A D Sagar; L A Pickering; P Sussman-Berger; W E Stewart; P B Sehgal
Journal:  Nucleic Acids Res       Date:  1981-01-10       Impact factor: 16.971

2.  Spontaneous production of gamma interferon and induced production of beta interferon by human T-lymphoblastoid cell lines.

Authors:  A G Morris; J Morser; A Meager
Journal:  Infect Immun       Date:  1982-02       Impact factor: 3.441

3.  High-level expression of an interferon alpha 2 gene cloned in phage M13mp7 and subsequent purification with a monoclonal antibody.

Authors:  P Slocombe; A Easton; P Boseley; D C Burke
Journal:  Proc Natl Acad Sci U S A       Date:  1982-09       Impact factor: 11.205

4.  Fate of secretory proteins trapped in oocytes of Xenopus laevis by disruption of the cytoskeleton or by imbalanced subunit synthesis.

Authors:  A Colman; J Morser; C Lane; J Besley; C Wylie; G Valle
Journal:  J Cell Biol       Date:  1981-12       Impact factor: 10.539

  4 in total

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