| Literature DB >> 22799084 |
Blanca Alanís-Garza1, Ricardo Salazar-Aranda, Rosalba Ramírez-Durón, Elvira Garza-González, Noemí Waksman de Torres.
Abstract
Bioassay-guided fractionation of the minor active fractions obtained from the root bark of Leucophyllumfrutescens (Berl.) I. M. Johnst. led to isolation from the n-hexane extract of a new compound with moderate activity against the H37Rv Mycobacterium tuberculosis strain (MIC 63 microg/mL), and low cytotoxicity, as shown by the IC5o against Vero cells. The compound was identified by 1D/2D NMR spectroscopy a s2',5"-dimethoxysesamin.Entities:
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Year: 2012 PMID： 22799084
Source DB: PubMed Journal: Nat Prod Commun ISSN： 1555-9475 Impact factor: 0.986