Literature DB >> 22798476

Using opioids to treat dyspnea in advanced COPD: attitudes and experiences of family physicians and respiratory therapists.

Joanne Young1, Margaret Donahue, Morag Farquhar, Cathy Simpson, Graeme Rocker.   

Abstract

OBJECTIVE: To explore the experiences of family physicians and respiratory therapists in treating advanced chronic obstructive pulmonary disease (COPD) and their attitudes to the use of opioids for dyspnea in this context.
DESIGN: Qualitative methodology using one-on-one semistructured interviews.
SETTING: Southern New Brunswick (St Stephen to Sussex). PARTICIPANTS: Ten family physicians and 8 respiratory therapists who worked in primary care settings.
METHODS: Participant interviews were audiorecorded, transcribed verbatim, coded conceptually, and thematically analyzed using interpretive description. MAIN
FINDINGS: Participants reported that patients with advanced COPD often suffered from inadequate control of their dyspnea in advanced stages and that they saw the potential value of opioids in this context; however, family physicians described discomfort prescribing opioids. Barriers included insufficient knowledge, lack of education and guidelines, and fear of censure. Those with palliative care experience tended to be more comfortable with opioid prescribing.
CONCLUSION: Findings suggest an important need to address barriers related to more effective treatment of refractory dyspnea in advanced COPD. Further, findings indicate these efforts should focus on effective palliation and innovative educational initiatives, as well as the development, promotion, and uptake of evidence-based practice guidelines related to prescribing opioids for these patients.

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Year:  2012        PMID: 22798476      PMCID: PMC3395547     

Source DB:  PubMed          Journal:  Can Fam Physician        ISSN: 0008-350X            Impact factor:   3.275


  9 in total

Review 1.  Managing dyspnea in patients with advanced chronic obstructive pulmonary disease: a Canadian Thoracic Society clinical practice guideline.

Authors:  Darcy D Marciniuk; Donna Goodridge; Paul Hernandez; Graeme Rocker; Meyer Balter; Pat Bailey; Gord Ford; Jean Bourbeau; Denis E O'Donnell; Francois Maltais; Richard A Mularski; Andrew J Cave; Irvin Mayers; Vicki Kennedy; Thomas K Oliver; Candice Brown
Journal:  Can Respir J       Date:  2011 Mar-Apr       Impact factor: 2.409

Review 2.  Global burden of COPD: risk factors, prevalence, and future trends.

Authors:  David M Mannino; A Sonia Buist
Journal:  Lancet       Date:  2007-09-01       Impact factor: 79.321

3.  An official American Thoracic Society clinical policy statement: palliative care for patients with respiratory diseases and critical illnesses.

Authors:  Paul N Lanken; Peter B Terry; Horace M Delisser; Bonnie F Fahy; John Hansen-Flaschen; John E Heffner; Mitchell Levy; Richard A Mularski; Molly L Osborne; Thomas J Prendergast; Graeme Rocker; William J Sibbald; Benjamin Wilfond; James R Yankaskas
Journal:  Am J Respir Crit Care Med       Date:  2008-04-15       Impact factor: 21.405

Review 4.  A systematic review of the use of opioids in the management of dyspnoea.

Authors:  A-L Jennings; A N Davies; J P T Higgins; J S R Gibbs; K E Broadley
Journal:  Thorax       Date:  2002-11       Impact factor: 9.139

5.  The healthcare needs of chronic obstructive pulmonary disease patients in the last year of life.

Authors:  Helena Elkington; Patrick White; Julia Addington-Hall; Roger Higgs; Polly Edmonds
Journal:  Palliat Med       Date:  2005-09       Impact factor: 4.762

Review 6.  American College of Chest Physicians consensus statement on the management of dyspnea in patients with advanced lung or heart disease.

Authors:  Donald A Mahler; Paul A Selecky; Christopher G Harrod; Joshua O Benditt; Virginia Carrieri-Kohlman; J Randall Curtis; Harold L Manning; Richard A Mularski; Basil Varkey; Margaret Campbell; Edward R Carter; Jun Ratunil Chiong; E Wesley Ely; John Hansen-Flaschen; Denis E O'Donnell; Alexander Waller
Journal:  Chest       Date:  2010-03       Impact factor: 9.410

7.  Once-daily opioids for chronic dyspnea: a dose increment and pharmacovigilance study.

Authors:  David C Currow; Christine McDonald; Sheila Oaten; Bernadette Kenny; Peter Allcroft; Peter Frith; Michael Briffa; Miriam J Johnson; Amy P Abernethy
Journal:  J Pain Symptom Manage       Date:  2011-03-31       Impact factor: 3.612

Review 8.  Palliation of dyspnoea in advanced COPD: revisiting a role for opioids.

Authors:  G Rocker; R Horton; D Currow; D Goodridge; J Young; S Booth
Journal:  Thorax       Date:  2009-10       Impact factor: 9.139

9.  Perceived barriers to guideline adherence: a survey among general practitioners.

Authors:  Marjolein Lugtenberg; Jako S Burgers; Casper F Besters; Dolly Han; Gert P Westert
Journal:  BMC Fam Pract       Date:  2011-09-22       Impact factor: 2.497

  9 in total
  21 in total

1.  Does nebulized fentanyl relieve dyspnea during exercise in healthy man?

Authors:  Houssam G Kotrach; Jean Bourbeau; Dennis Jensen
Journal:  J Appl Physiol (1985)       Date:  2015-03-12

2.  Perspectives of patients, family caregivers and physicians about the use of opioids for refractory dyspnea in advanced chronic obstructive pulmonary disease.

Authors:  Graeme Rocker; Joanne Young; Margaret Donahue; Morag Farquhar; Catherine Simpson
Journal:  CMAJ       Date:  2012-04-23       Impact factor: 8.262

Review 3.  Inadequate Palliative Care in Chronic Lung Disease. An Issue of Health Care Inequality.

Authors:  Crystal E Brown; Nancy S Jecker; J Randall Curtis
Journal:  Ann Am Thorac Soc       Date:  2016-03

4.  Incident opioid drug use among older adults with chronic obstructive pulmonary disease: a population-based cohort study.

Authors:  Nicholas T Vozoris; Xuesong Wang; Hadas D Fischer; Andrea S Gershon; Chaim M Bell; Sudeep S Gill; Denis E O'Donnell; Peter C Austin; Anne L Stephenson; Paula A Rochon
Journal:  Br J Clin Pharmacol       Date:  2015-10-02       Impact factor: 4.335

5.  Effect of Sustained-Release Morphine for Refractory Breathlessness in Chronic Obstructive Pulmonary Disease on Health Status: A Randomized Clinical Trial.

Authors:  Cornelia A Verberkt; Marieke H J van den Beuken-van Everdingen; Jos M G A Schols; Niels Hameleers; Emiel F M Wouters; Daisy J A Janssen
Journal:  JAMA Intern Med       Date:  2020-10-01       Impact factor: 21.873

6.  Opioid therapy for refractory dyspnea in patients with advanced chronic obstructive pulmonary disease: patients' experiences and outcomes.

Authors:  Graeme M Rocker; A Catherine Simpson; Robert Horton; Tasnim Sinuff; Jillian Demmons; Paul Hernandez; Darcy Marciniuk
Journal:  CMAJ Open       Date:  2013-01-24

7.  A Qualitative Study of Pulmonary and Palliative Care Clinician Perspectives on Early Palliative Care in Chronic Obstructive Pulmonary Disease.

Authors:  Anand S Iyer; James Nicholas Dionne-Odom; Dina M Khateeb; Lanier O'Hare; Rodney O Tucker; Cynthia J Brown; Mark T Dransfield; Marie A Bakitas
Journal:  J Palliat Med       Date:  2019-10-29       Impact factor: 2.947

8.  Safety of benzodiazepines and opioids in very severe respiratory disease: national prospective study.

Authors:  Magnus P Ekström; Anna Bornefalk-Hermansson; Amy P Abernethy; David C Currow
Journal:  BMJ       Date:  2014-01-30

9.  Predictors of Morphine Efficacy for Dyspnea in Inpatients with Chronic Obstructive Pulmonary Disease: A Secondary Analysis of JORTC-PAL 07.

Authors:  Yoshinobu Matsuda; Tatsuya Morita; Hirotaka Matsumoto; Keita Hosoi; Kayo Kusama; Yasuo Kohashi; Hiroshi Morishita; Sawako Kaku; Keisukie Ariyoshi; Shunsuke Oyamada; Yoshikazu Inoue; Satoru Iwase; Takuhiro Yamaguchi; Mitsunori Nishikawa
Journal:  Palliat Med Rep       Date:  2021-01-07

10.  Implementation of multiple-domain covering computerized decision support systems in primary care: a focus group study on perceived barriers.

Authors:  Marjolein Lugtenberg; Jan-Willem Weenink; Trudy van der Weijden; Gert P Westert; Rudolf B Kool
Journal:  BMC Med Inform Decis Mak       Date:  2015-10-12       Impact factor: 2.796

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