PURPOSE: The purpose of this study was to evaluate the incidence and predictors of seed migration after transperineal interstitial prostate brachytherapy. MATERIALS AND METHODS: From March 2007 to March 2011, 121 patients with stage T1-T2 prostate cancer underwent transperineal interstitial prostate brachytherapy. Pre-planning was performed 3 weeks prior to implantation, and the implants were inserted using the standard parallel needle insertion technique. All patients underwent a series of radiographs [chest radiography, kidney-ureter-bladder (KUB) radiography, and a CT scan] to assess whether seed migration had occurred on postoperative days 1 and 30, and 12 months. RESULTS: Seed migration occurred in 31 (25.6 %) of 121 patients. A total of 51 of 7,883 (0.65 %) implanted seeds migrated. Migration was detected on postoperative day 1 in 16 patients, day 30 in 13 patients and at 12 months in 4 patients (migration occurred at different times in 2 patients). The migrated seeds were found in the lungs, pelvis, heart, mediastinum, kidney, inguinal canal, liver and sacrum. The number of needles was a statistically significant factor in seed migration. CONCLUSIONS: The seeds migrated to many organs. No decrease in the dose administered to the prostate or adverse effects associated with seed migration were noted.
PURPOSE: The purpose of this study was to evaluate the incidence and predictors of seed migration after transperineal interstitial prostate brachytherapy. MATERIALS AND METHODS: From March 2007 to March 2011, 121 patients with stage T1-T2 prostate cancer underwent transperineal interstitial prostate brachytherapy. Pre-planning was performed 3 weeks prior to implantation, and the implants were inserted using the standard parallel needle insertion technique. All patients underwent a series of radiographs [chest radiography, kidney-ureter-bladder (KUB) radiography, and a CT scan] to assess whether seed migration had occurred on postoperative days 1 and 30, and 12 months. RESULTS: Seed migration occurred in 31 (25.6 %) of 121 patients. A total of 51 of 7,883 (0.65 %) implanted seeds migrated. Migration was detected on postoperative day 1 in 16 patients, day 30 in 13 patients and at 12 months in 4 patients (migration occurred at different times in 2 patients). The migrated seeds were found in the lungs, pelvis, heart, mediastinum, kidney, inguinal canal, liver and sacrum. The number of needles was a statistically significant factor in seed migration. CONCLUSIONS: The seeds migrated to many organs. No decrease in the dose administered to the prostate or adverse effects associated with seed migration were noted.
Authors: Brian J Davis; John F Bresnahan; Scott L Stafford; Barry L Karon; Bernard F King; Torrence M Wilson Journal: J Urol Date: 2002-09 Impact factor: 7.450
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Authors: Jeffrey S Eshleman; Brian J Davis; Thomas M Pisansky; Torrence M Wilson; Michael G Haddock; Bernard F King; Charles H Darby; Wayne N Lajoie; Ann L Oberg Journal: Int J Radiat Oncol Biol Phys Date: 2004-06-01 Impact factor: 7.038
Authors: Philipp Maletzki; Christoph Schwab; Patrick Markart; Daniel Engeler; Johann Schiefer; Ludwig Plasswilm; Hans-Peter Schmid Journal: Prostate Int Date: 2017-09-30