Literature DB >> 22796737

Comparison between primary angioplasty and thrombolytic therapy on erectile dysfunction after acute ST elevation myocardial infarction.

Ramazan Akdemir1, Ozlem Karakurt, Salih Orcan, Nihat Karakoyunlu, Mustafa Mucahit Balci, Levent Sağnak, Hamit Ersoy, Mehmet Bulent Vatan, Harun Kilic, Ekrem Yeter.   

Abstract

Acute ST elevation myocardial infarction has high mortality and morbidity rates. The majority of patients with this condition face erectile dysfunction in addition to other health problems. In this study, we aimed to investigate the effects of two different reperfusion strategies, primary angioplasty and thrombolytic therapy, on the prevalence of erectile dysfunction after acute myocardial infarction. Of the 71 patients matching the selection criteria, 45 were treated with primary coronary angioplasty with stenting, and 26 were treated with thrombolytic agents. Erectile function was evaluated using the International Index of Erectile Function in the hospital to characterize each patient's sexual function before the acute myocardial infarction and 6 months after the event. The time required to restore blood flow to the artery affected by the infarct was found to be associated with the occurrence of erectile dysfunction after acute myocardial infarction. The increase in the prevalence of erectile dysfunction after acute myocardial infarction was 44.4% in the angioplasty group and 76.9% in the thrombolytic therapy group (P=0.008). In conclusion, this study has shown that reducing the time of reperfusion decreases the erectile dysfunction prevalence, and primary angioplasty is superior to thrombolytic therapy for decreasing the prevalence of erectile dysfunction after acute myocardial infarction.

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Year:  2012        PMID: 22796737      PMCID: PMC3734985          DOI: 10.1038/aja.2012.41

Source DB:  PubMed          Journal:  Asian J Androl        ISSN: 1008-682X            Impact factor:   3.285


  16 in total

1.  Is erectile dysfunction the "tip of the iceberg" of a systemic vascular disorder?

Authors:  Piero Montorsi; Francesco Montorsi; Claude C Schulman
Journal:  Eur Urol       Date:  2003-09       Impact factor: 20.096

2.  Does severity of ischemic coronary disease correlate with erectile function?

Authors:  A Greenstein; J Chen; H Miller; H Matzkin; Y Villa; Z Braf
Journal:  Int J Impot Res       Date:  1997-09       Impact factor: 2.896

3.  The international index of erectile function (IIEF): a multidimensional scale for assessment of erectile dysfunction.

Authors:  R C Rosen; A Riley; G Wagner; I H Osterloh; J Kirkpatrick; A Mishra
Journal:  Urology       Date:  1997-06       Impact factor: 2.649

4.  [Erectile dysfunction: a marker for myocardial perfusion impairment?].

Authors:  Juarez Ortiz; Sergio Tranchesi Ortiz; Claudia Gianini Monaco; Cristina Harumi Yamashita; Miriam Cássia Mendes Moreira; Carlos Alberto F Monaco
Journal:  Arq Bras Cardiol       Date:  2005-11-07       Impact factor: 2.000

Review 5.  Cardiac disease, anxiety, and sexual functioning.

Authors:  S Friedman
Journal:  Am J Cardiol       Date:  2000-07-20       Impact factor: 2.778

Review 6.  Metabolic syndrome and sexual dysfunction.

Authors:  Bilal Chughtai; Richard K Lee; Alexis E Te; Steven A Kaplan
Journal:  Curr Opin Urol       Date:  2011-11       Impact factor: 2.309

7.  ACC/AHA guidelines for the management of patients with ST-elevation myocardial infarction--executive summary. A report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to revise the 1999 guidelines for the management of patients with acute myocardial infarction).

Authors:  Elliott M Antman; Daniel T Anbe; Paul Wayne Armstrong; Eric R Bates; Lee A Green; Mary Hand; Judith S Hochman; Harlan M Krumholz; Frederick G Kushner; Gervasio A Lamas; Charles J Mullany; Joseph P Ornato; David L Pearle; Michael A Sloan; Sidney C Smith
Journal:  J Am Coll Cardiol       Date:  2004-08-04       Impact factor: 24.094

Review 8.  Primary angioplasty versus intravenous thrombolytic therapy for acute myocardial infarction: a quantitative review of 23 randomised trials.

Authors:  Ellen C Keeley; Judith A Boura; Cindy L Grines
Journal:  Lancet       Date:  2003-01-04       Impact factor: 79.321

9.  Relationship between erectile dysfunction and silent myocardial ischemia in apparently uncomplicated type 2 diabetic patients.

Authors:  Carmine Gazzaruso; Stefano Giordanetti; Emanuela De Amici; Gianandrea Bertone; Colomba Falcone; Diego Geroldi; Pietro Fratino; Sebastiano B Solerte; Adriana Garzaniti
Journal:  Circulation       Date:  2004-06-21       Impact factor: 29.690

10.  Should erectile dysfunction be considered as a marker for acute myocardial infarction? Results from a retrospective cohort study.

Authors:  W A Blumentals; A Gomez-Caminero; S Joo; V Vannappagari
Journal:  Int J Impot Res       Date:  2004-08       Impact factor: 2.896

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