BACKGROUND: Pulse oximetry has become an important tool in evaluating, and monitoring pulmonary diseases, but the knowledge about arterial oxygen saturation (SpO(2)) values in a general population is limited. The aim of this study was to describe the distribution of low pulse oximetry values in a general adult population and their association with certain predictors. METHODS: A cross-sectional population based survey was performed in Tromsø, Norway, in 2007-2008. Valid SpO(2) and pre-bronchodilator spirometry was recorded in 6317 participants aged 38-87 years (57% women). Resting SpO(2) ≤95% was defined as an abnormal value. Predictors of SpO(2) ≤95% with p < 0.05 were entered into a binary multivariable logistic regression. RESULTS: The prevalence of SpO(2) ≤95% was 6.3%. The strongest predictors in the logistic regression were increased body mass index (BMI) (OR of BMI ≥35 = 6.2, CI(4.2, 9.2)), and reduced forced expiratory volume in 1 s (FEV(1)) % predicted (OR of FEV1% predicted <50 = 4.1, CI(2.5, 6.7)), followed by increased age, male gender, and smoking (p < 0.001). Other significant predictors were elevated C-reactive protein (CRP) (p < 0.005), former smoking, breathlessness and elevated hemoglobin (p < 0.01). CONCLUSION: Airflow limitation and other known signs of pulmonary diseases were, as expected, strongly associated with decreased oxygen saturation. Obesity was also a strong predictor of low SpO(2), and should be included among possible explanations when low SpO(2) values are encountered.
BACKGROUND: Pulse oximetry has become an important tool in evaluating, and monitoring pulmonary diseases, but the knowledge about arterial oxygen saturation (SpO(2)) values in a general population is limited. The aim of this study was to describe the distribution of low pulse oximetry values in a general adult population and their association with certain predictors. METHODS: A cross-sectional population based survey was performed in Tromsø, Norway, in 2007-2008. Valid SpO(2) and pre-bronchodilator spirometry was recorded in 6317 participants aged 38-87 years (57% women). Resting SpO(2) ≤95% was defined as an abnormal value. Predictors of SpO(2) ≤95% with p < 0.05 were entered into a binary multivariable logistic regression. RESULTS: The prevalence of SpO(2) ≤95% was 6.3%. The strongest predictors in the logistic regression were increased body mass index (BMI) (OR of BMI ≥35 = 6.2, CI(4.2, 9.2)), and reduced forced expiratory volume in 1 s (FEV(1)) % predicted (OR of FEV1% predicted <50 = 4.1, CI(2.5, 6.7)), followed by increased age, male gender, and smoking (p < 0.001). Other significant predictors were elevated C-reactive protein (CRP) (p < 0.005), former smoking, breathlessness and elevated hemoglobin (p < 0.01). CONCLUSION: Airflow limitation and other known signs of pulmonary diseases were, as expected, strongly associated with decreased oxygen saturation. Obesity was also a strong predictor of low SpO(2), and should be included among possible explanations when low SpO(2) values are encountered.
Authors: J Michael Wells; Raul San Jose Estepar; Merry-Lynn N McDonald; Surya P Bhatt; Alejandro A Diaz; William C Bailey; Francine L Jacobson; Mark T Dransfield; George R Washko; Barry J Make; Richard Casaburi; Edwin J R van Beek; Eric A Hoffman; Frank C Sciurba; James D Crapo; Edwin K Silverman; Craig P Hersh Journal: BMC Pulm Med Date: 2016-12-01 Impact factor: 3.317
Authors: Merry-Lynn N McDonald; Michael H Cho; Inga-Cecilie Sørheim; Sharon M Lutz; Peter J Castaldi; David A Lomas; Harvey O Coxson; Lisa D Edwards; William MacNee; Jørgen Vestbo; Julie C Yates; Alvar Agusti; Peter M A Calverley; Bartolome Celli; Courtney Crim; Stephen I Rennard; Emiel F M Wouters; Per Bakke; Ruth Tal-Singer; Bruce E Miller; Amund Gulsvik; Richard Casaburi; J Michael Wells; Elizabeth A Regan; Barry J Make; John E Hokanson; Christoph Lange; James D Crapo; Terri H Beaty; Edwin K Silverman; Craig P Hersh Journal: Am J Respir Cell Mol Biol Date: 2014-11 Impact factor: 6.914