Literature DB >> 22794253

A feud that wasn't: acetylcholine evokes dopamine release in the striatum.

D James Surmeier1, Ann M Graybiel.   

Abstract

In this issue of Neuron, Threlfell et al. (2012) report that synchronous activation of cholinergic interneurons evokes striatal dopamine release by activating presynaptic nicotinic acetylcholine receptors. These findings call for a fundamental reevaluation of the long-standing view that dopamine and acetylcholine "feud" over control of striatal circuitry.
Copyright © 2012 Elsevier Inc. All rights reserved.

Entities:  

Year:  2012        PMID: 22794253      PMCID: PMC3461267          DOI: 10.1016/j.neuron.2012.06.028

Source DB:  PubMed          Journal:  Neuron        ISSN: 0896-6273            Impact factor:   17.173


  14 in total

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Authors:  B D Bennett; C J Wilson
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Review 7.  Optogenetic studies of nicotinic contributions to cholinergic signaling in the central nervous system.

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