Literature DB >> 22794094

The need to address the burden of musculoskeletal conditions.

Anthony D Woolf1, Jo Erwin, Lyn March.   

Abstract

Musculoskeletal conditions are common in men and women of all ages across all socio-demographic strata of society. They are the most common cause of severe long-term pain and physical disability and affect hundreds of millions of people around the world. They impact on all aspects of life through pain and by limiting activities of daily living typically by affecting dexterity and mobility. They affect one in four adults across Europe [1]. Musculoskeletal conditions have an enormous economic impact on society through both direct health expenditure related to treating the sequelae of the conditions and indirectly through loss of productivity. The prevalence of many of these conditions increases markedly with age, and many are affected by lifestyle factors, such as obesity and lack of physical activity. The burden of these conditions is therefore predicted to increase, in particular in developing countries. The impact on individuals and society of the major musculoskeletal conditions is reviewed and effective prevention, treatment and rehabilitation considered. The need to recognise musculoskeletal conditions as a global public health priority is discussed.
Copyright © 2012. Published by Elsevier Ltd.

Entities:  

Mesh:

Year:  2012        PMID: 22794094     DOI: 10.1016/j.berh.2012.03.005

Source DB:  PubMed          Journal:  Best Pract Res Clin Rheumatol        ISSN: 1521-6942            Impact factor:   4.098


  67 in total

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Review 3.  Surgical Burden of Musculoskeletal Conditions in Low- and Middle-Income Countries.

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5.  Musculoskeletal Function and Obesity: Implications for Physical Activity.

Authors:  Sarah P Shultz; Nuala M Byrne; Andrew P Hills
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6.  Health care utilisation in subjects with osteoarthritis, chronic back pain and osteoporosis aged 65 years and more: mediating effects of limitations in activities of daily living, pain intensity and mental diseases.

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Journal:  Wien Med Wochenschr       Date:  2014-01-28

7.  Mechanotransduction in primary human osteoarthritic chondrocytes is mediated by metabolism of energy, lipids, and amino acids.

Authors:  Donald L Zignego; Jonathan K Hilmer; Ronald K June
Journal:  J Biomech       Date:  2015-10-31       Impact factor: 2.712

Review 8.  The neurobiology of skeletal pain.

Authors:  Patrick W Mantyh
Journal:  Eur J Neurosci       Date:  2014-02       Impact factor: 3.386

9.  Inhibition of 4-aminobutyrate aminotransferase protects against injury-induced osteoarthritis in mice.

Authors:  Jie Shen; Cuicui Wang; Jun Ying; Taotao Xu; Audrey McAlinden; Regis J O'Keefe
Journal:  JCI Insight       Date:  2019-09-19

10.  RNA Sequencing Reveals Interacting Key Determinants of Osteoarthritis Acting in Subchondral Bone and Articular Cartilage: Identification of IL11 and CHADL as Attractive Treatment Targets.

Authors:  Margo Tuerlings; Marcella van Hoolwerff; Evelyn Houtman; Eka H E D Suchiman; Nico Lakenberg; Hailiang Mei; Enrike H M J van der Linden; Rob R G H H Nelissen; Yolande Y F M Ramos; Rodrigo Coutinho de Almeida; Ingrid Meulenbelt
Journal:  Arthritis Rheumatol       Date:  2021-03-21       Impact factor: 10.995

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