Literature DB >> 22793938

Pathobiologic mechanisms of chronic obstructive pulmonary disease.

Anthony Tam1, Don D Sin.   

Abstract

COPD is a worldwide public health problem that reduces the quality of life. The exact pathways by which CS and other environmental toxins produce COPD are not known. Currently, the leading candidates are (1) the protease-antiprotease hypothesis, (2) the Dutch hypothesis, (3) the British hypothesis, and the (4) autoimmunity hypothesis. Given the heterogeneity of the disease (and phenotypes), it is probably unrealistic that one pathway will fully explain COPD pathophysiology.
Copyright © 2012 Elsevier Inc. All rights reserved.

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Year:  2012        PMID： 22793938     DOI： 10.1016/j.mcna.2012.04.012

Source DB:  PubMed          Journal:  Med Clin North Am        ISSN： 0025-7125            Impact factor:   5.456


  18 in total

Review 1.  Pharmacological approaches to regulate neutrophil activity.

Authors:  G R Tintinger; R Anderson; C Feldman
Journal:  Semin Immunopathol       Date:  2013-03-15       Impact factor: 9.623

2.  Cigarette Smoke Activates NOTCH3 to Promote Goblet Cell Differentiation in Human Airway Epithelial Cells.

Authors:  Manish Bodas; Andrew R Moore; Bharathiraja Subramaniyan; Constantin Georgescu; Jonathan D Wren; Willard M Freeman; Brent R Brown; Jordan P Metcalf; Matthew S Walters
Journal:  Am J Respir Cell Mol Biol       Date:  2021-04       Impact factor: 6.914

3.  Activation of NOTCH1 or NOTCH3 signaling skews human airway basal cell differentiation toward a secretory pathway.

Authors:  Kazunori Gomi; Vanessa Arbelaez; Ronald G Crystal; Matthew S Walters
Journal:  PLoS One       Date:  2015-02-20       Impact factor: 3.240

4.  Alterations in the expression of the NF-κB family member RelB as a novel marker of cardiovascular outcomes during acute exacerbations of chronic obstructive pulmonary disease.

Authors:  Laura Labonté; Patrick Coulombe; Michela Zago; Jean Bourbeau; Carolyn J Baglole
Journal:  PLoS One       Date:  2014-11-19       Impact factor: 3.240

5.  Oxidant-antioxidant balance in the blood of patients with chronic obstructive pulmonary disease after smoking cessation.

Authors:  Alina Woźniak; Dariusz Górecki; Michał Szpinda; Celestyna Mila-Kierzenkowska; Bartosz Woźniak
Journal:  Oxid Med Cell Longev       Date:  2013-09-05       Impact factor: 6.543

6.  Generation of a human airway epithelium derived basal cell line with multipotent differentiation capacity.

Authors:  Matthew S Walters; Kazunori Gomi; Beth Ashbridge; Malcolm A S Moore; Vanessa Arbelaez; Jonna Heldrich; Bi-Sen Ding; Shahin Rafii; Michelle R Staudt; Ronald G Crystal
Journal:  Respir Res       Date:  2013-12-03

7.  Central airways remodeling in COPD patients.

Authors:  Laura Pini; Valentina Pinelli; Denise Modina; Michela Bezzi; Laura Tiberio; Claudio Tantucci
Journal:  Int J Chron Obstruct Pulmon Dis       Date:  2014-09-01

8.  Smoking accelerates aging of the small airway epithelium.

Authors:  Matthew S Walters; Bishnu P De; Jacqueline Salit; Lauren J Buro-Auriemma; Timothy Wilson; Allison M Rogalski; Lindsay Lief; Neil R Hackett; Michelle R Staudt; Ann E Tilley; Ben-Gary Harvey; Robert J Kaner; Jason G Mezey; Beth Ashbridge; Malcolm A S Moore; Ronald G Crystal
Journal:  Respir Res       Date:  2014-09-24

Review 9.  Lung inflammation caused by inhaled toxicants: a review.

Authors:  John Wong; Bruce E Magun; Lisa J Wood
Journal:  Int J Chron Obstruct Pulmon Dis       Date:  2016-06-23

10.  SIRT1/FoxO3 axis alteration leads to aberrant immune responses in bronchial epithelial cells.

Authors:  Serena Di Vincenzo; Irene H Heijink; Jacobien A Noordhoek; Chiara Cipollina; Liboria Siena; Andreina Bruno; Maria Ferraro; Dirkje S Postma; Mark Gjomarkaj; Elisabetta Pace
Journal:  J Cell Mol Med       Date:  2018-02-07       Impact factor: 5.310
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