Literature DB >> 22791836

Dependence and psychosis with 4-methylmethcathinone (mephedrone) use.

N Bajaj1, D Mullen, S Wylie.   

Abstract

'Legal highs' are recreational drugs sold over the internet and the so-called 'head shops' all over the UK. They are freely available to buy and use as they are not covered by the Misuse of Drugs Act 1971. Mephedrone (4-methylmethcathinone) was sold as a 'legal high' until 17 April 2010 when it was made a class B drug under the Misuse of Drugs Act 1971. Numerous deaths and self-harm has been associated with mephedrone use. Effects of mephedrone are reported to be empathogenic similar to 3,4-methylenedioxymethamphetamine (MDMA, ecstasy) and stimulant properties similar to cocaine. Not much is known of the effects of mephedrone on mental health. We present a case of dependence and psychosis in a patient using mephedrone (4-methylmethcathinone). The patient needed inpatient hospital care, was treated with antipsychotic olanzapine and recovered well.

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Year:  2010        PMID: 22791836      PMCID: PMC3027483          DOI: 10.1136/bcr.02.2010.2780

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  6 in total

Review 1.  The toxicology of bath salts: a review of synthetic cathinones.

Authors:  Jane M Prosser; Lewis S Nelson
Journal:  J Med Toxicol       Date:  2012-03

2.  Mephedrone in adolescent rats: residual memory impairment and acute but not lasting 5-HT depletion.

Authors:  Craig P Motbey; Emily Karanges; Kong M Li; Shane Wilkinson; Adam R Winstock; John Ramsay; Callum Hicks; Michael D Kendig; Naomi Wyatt; Paul D Callaghan; Iain S McGregor
Journal:  PLoS One       Date:  2012-09-18       Impact factor: 3.240

3.  Severe Psychosis, Drug Dependence, and Hepatitis C Related to Slamming Mephedrone.

Authors:  Helen Dolengevich-Segal; Beatriz Rodríguez-Salgado; Jorge Gómez-Arnau; Daniel Sánchez-Mateos
Journal:  Case Rep Psychiatry       Date:  2016-05-10

Review 4.  Novel Psychoactive Substances-Recent Progress on Neuropharmacological Mechanisms of Action for Selected Drugs.

Authors:  Zurina Hassan; Oliver G Bosch; Darshan Singh; Suresh Narayanan; B Vicknasingam Kasinather; Erich Seifritz; Johannes Kornhuber; Boris B Quednow; Christian P Müller
Journal:  Front Psychiatry       Date:  2017-08-18       Impact factor: 4.157

5.  Central Effects of the Designer Drug Mephedrone in Mice-Basic Studies.

Authors:  Anna Serefko; Gabriela Bielecka-Papierz; Sylwia Talarek; Aleksandra Szopa; Piotr Skałecki; Bernadeta Szewczyk; Maria Radziwoń-Zaleska; Ewa Poleszak
Journal:  Brain Sci       Date:  2022-01-30

6.  "Bath salts" induced severe reversible cardiomyopathy.

Authors:  Kamesh Sivagnanam; Dhara Chaudari; Pablo Lopez; Michael E Sutherland; Vijay K Ramu
Journal:  Am J Case Rep       Date:  2013-07-31
  6 in total

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