Literature DB >> 22791006

Treatment of delayed neurological deficits after surgical repair of thoracic aortic aneurysm.

Yohsuke Yanase1, Nobuyoshi Kawaharada, Toshiyuki Maeda, Tetsuya Koyanagi, Toshiro Ito, Yoshihiko Kurimoto, Tetsuya Higami.   

Abstract

Delayed neurologic deficits, paraplegia and paraparesis, are devastating complications after repair of a descending thoracic and thoracoabdominal aortic aneurysm (TAAA). A treatment protocol has not been established, although strategies such as cerebrospinal fluid (CSF) drainage, maintaining blood pressure and medication have been described. Cerebrospinal drain status /oxygen delivery/patient status (COPS) therapy for delayed neurological deficit can improve spinal cord ischemia through reducing intraspinal pressure, improving oxygen delivery and maintaining high blood pressure. We describe one patient (Case 1), in whom descending thoracic and abdominal aortic aneurysms were treated by endovascular aortic repair, and another (Case 2) with Crawford type II TAAA, who developed delayed neurological deficits that were treated with immediate COPS therapy (Modified Tarlov scale; Case 1, improved from 2 to 4; Case 2, from 0 to 4). These findings indicate the benefit of COPS for treating delayed neurological deficits after descending thoracic and TAAA.

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Year:  2012        PMID: 22791006     DOI: 10.5761/atcs.cr.11.01741

Source DB:  PubMed          Journal:  Ann Thorac Cardiovasc Surg        ISSN: 1341-1098            Impact factor:   1.520


  1 in total

1.  The SDF-1/CXCR4 axis promotes recovery after spinal cord injury by mediating bone marrow-derived from mesenchymal stem cells.

Authors:  Guo-Dong Wang; Yi-Xun Liu; Xiao Wang; Yong-Le Zhang; Ya-Dong Zhang; Feng Xue
Journal:  Oncotarget       Date:  2017-02-14
  1 in total

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