Sang Beom Han1, Hee Kyung Yang, Joon Young Hyon, Jeong-Min Hwang. 1. Department of Ophthalmology, Seoul National University College of Medicine, Seoul National University Bundang Hospital, 166 Gumiro, Bundang-gu, Seongnam, Gyeonggi-do 463-707, Korea.
Abstract
BACKGROUND: To compare the symptom scores of children with those of adults with the same degree of mild ocular surface signs. METHODS: This study included patients with at least one ocular surface symptom and sign. Data obtained from 45 subjects aged 8.79 ± 2.95 yr (Mean ± SD) (pediatric group) and 45 adults aged 52.87 ± 10.87 yr (adult group) who were matched to each pediatric patient based on ocular surface signs were analyzed. Demographic data including age and sex; parameters of ocular surface signs including fluorescein staining score, tear film breakup time and Schirmer test score; symptom scores including ocular surface disease index (OSDI) and visual analog scale (VAS) were assessed and compared between the two groups. RESULTS: Significant differences emerged in sex ratio as well as in age between the two groups (P < 0.001, for both). Regarding ocular surface signs and tear film tests, the study revealed no significant differences in fluorescein staining score (1.44 ± 1.95 vs. 1.40 ± 1.68 P = 0.913), tear film break up time (4.96 ± 1.94 vs. 3.82 ± 1.85 s, P = 0.612) and Schirmer score (12.79 ± 9.05 vs. 10.11 ± 8.45 mm / 5 min, P = 0.370). Regarding dry eye symptoms, both OSDI and VAS were significantly lower in the pediatric group (P = 0.001 and < 0.001, respectively) than in the adult group. CONCLUSION: Pediatric patients with mild ocular surface damage may report fewer dry eye symptoms compared to adult patients with similar stages of ocular surface damage.
BACKGROUND: To compare the symptom scores of children with those of adults with the same degree of mild ocular surface signs. METHODS: This study included patients with at least one ocular surface symptom and sign. Data obtained from 45 subjects aged 8.79 ± 2.95 yr (Mean ± SD) (pediatric group) and 45 adults aged 52.87 ± 10.87 yr (adult group) who were matched to each pediatric patient based on ocular surface signs were analyzed. Demographic data including age and sex; parameters of ocular surface signs including fluorescein staining score, tear film breakup time and Schirmer test score; symptom scores including ocular surface disease index (OSDI) and visual analog scale (VAS) were assessed and compared between the two groups. RESULTS: Significant differences emerged in sex ratio as well as in age between the two groups (P < 0.001, for both). Regarding ocular surface signs and tear film tests, the study revealed no significant differences in fluorescein staining score (1.44 ± 1.95 vs. 1.40 ± 1.68 P = 0.913), tear film break up time (4.96 ± 1.94 vs. 3.82 ± 1.85 s, P = 0.612) and Schirmer score (12.79 ± 9.05 vs. 10.11 ± 8.45 mm / 5 min, P = 0.370). Regarding dry eye symptoms, both OSDI and VAS were significantly lower in the pediatric group (P = 0.001 and < 0.001, respectively) than in the adult group. CONCLUSION: Pediatric patients with mild ocular surface damage may report fewer dry eye symptoms compared to adult patients with similar stages of ocular surface damage.
Authors: Sang Beom Han; Joon Young Hyon; Won Ryang Wee; Jin Hak Lee; Yun Jong Lee; Pil-Young Yun Journal: Acta Ophthalmol Date: 2010-11 Impact factor: 3.761
Authors: Edoardo Villani; Marika Dello Strologo; Francesco Pichi; Saverio V Luccarelli; Stefano De Cillà; Massimiliano Serafino; Paolo Nucci Journal: Medicine (Baltimore) Date: 2015-10 Impact factor: 1.817