| Literature DB >> 22790234 |
Sven Stadlbauer1, Ken Ohmori, Fumihiko Hattori, Keisuke Suzuki.
Abstract
Concise synthesis of (-)-epicatechin and its 3-O-gallate is described, illustrating efficacy of the new strategy for catechin-class polyphenols based on assembly of lithiated fluorobenzene and epoxy alcohol followed by a pyran cyclization. 1,3,5-Trifluorobenzene serves as the A-ring equivalent for functionalization and the pyran annulation.Entities:
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Year: 2012 PMID： 22790234 DOI： 10.1039/c2cc33704e
Source DB: PubMed Journal: Chem Commun (Camb) ISSN： 1359-7345 Impact factor: 6.222