Literature DB >> 22789867

Aureolic acids from a marine-derived Streptomyces sp. WBF16.

Jiansheng Lu1, Yihua Ma, Jianjia Liang, Yingying Xing, Tao Xi, Yuanyuan Lu.   

Abstract

A marine-derived actinomycete (Streptomyces sp. WBF16) exhibiting antitumor activities was investigated. The strain was identified using morphological, biochemical and genetic techniques. 16S rDNA sequence of the isolate indicated that it was most closely related to Streptomyces coelicolor A3 (2). Furthermore, a new aureolic acid (Chromomycin B, 1), along with Chromomycin A(2) (2) and Chromomycin A(3) (3) were isolated from its secondary metabolites. Their structures were determined by chemical and spectroscopic methods including 1D, 2D NMR and HRMS. Compounds 1-3 showed strong cytotoxicity against SGC7901, HepG2, A549, HCT116 and COC1 and HUVEC.
Copyright © 2012 Elsevier GmbH. All rights reserved.

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Year:  2012        PMID： 22789867     DOI： 10.1016/j.micres.2012.06.001

Source DB:  PubMed          Journal:  Microbiol Res        ISSN： 0944-5013            Impact factor:   5.415


  5 in total

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Journal:  Curr Microbiol       Date:  2022-08-24       Impact factor: 2.343

2.  An "olivomycin A" derivative from a sponge-associated Streptomyces sp. strain SP 85.

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Journal:  3 Biotech       Date:  2019-11-07       Impact factor: 2.406

Review 3.  Marine Natural Products: A Source of Novel Anticancer Drugs.

Authors:  Shaden A M Khalifa; Nizar Elias; Mohamed A Farag; Lei Chen; Aamer Saeed; Mohamed-Elamir F Hegazy; Moustafa S Moustafa; Aida Abd El-Wahed; Saleh M Al-Mousawi; Syed G Musharraf; Fang-Rong Chang; Arihiro Iwasaki; Kiyotake Suenaga; Muaaz Alajlani; Ulf Göransson; Hesham R El-Seedi
Journal:  Mar Drugs       Date:  2019-08-23       Impact factor: 5.118

Review 4.  Natural Products from Actinobacteria as a Potential Source of New Therapies Against Colorectal Cancer: A Review.

Authors:  Yadollah Bahrami; Sasan Bouk; Elham Kakaei; Mohammad Taheri
Journal:  Front Pharmacol       Date:  2022-07-11       Impact factor: 5.988

5.  Chromomycin A2 induces autophagy in melanoma cells.

Authors:  Larissa Alves Guimarães; Paula Christine Jimenez; Thiciana da Silva Sousa; Hozana Patrícia S Freitas; Danilo Damasceno Rocha; Diego Veras Wilke; Jesús Martín; Fernando Reyes; Otília Deusdênia Loiola Pessoa; Letícia Veras Costa-Lotufo
Journal:  Mar Drugs       Date:  2014-12-04       Impact factor: 5.118
  5 in total

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