Literature DB >> 22787504

Septic and aseptic complications of corticosteroid injections: an assessment of 278 cases reviewed by expert commissions and mediation boards from 2005 to 2009.

Christian Holland1, Lothar Jaeger, Ulrich Smentkowski, Beate Weber, Christina Otto.   

Abstract

BACKGROUND: Local corticosteroid injections can have serious septic and aseptic complications.
METHODS: From 2005 to 2009, medical expert committees and mediation boards reviewed 1528 cases of alleged treatment errors relating to injections.
RESULTS: 278 cases were identified in which complications arose after local glucocorticosteroid injections. The injections were intra-articular, paravertebral, intramuscular, and at other sites. In 39.6% of cases, treatment errors or patient information errors of the following types were found: aseptic technique was not maintained, injections were performed in the absence of an indication, time intervals between injections were too short, excessive doses were administered, infections were not diagnosed, erroneous injections were performed, patients were not informed of the risks, and there were errors of organization and documentation.
CONCLUSIONS: Injections of glucocorticosteroids must be performed in strict adherence to the manufacturer's instructions with respect to the composition of the solution to be injected, the quantity per injection, and the intervals between injections. Repeated injections with too little time between them raise the risk of infection. Physicians should pay more attention to this fact, particularly when deciding on the indication for paravertebral injections. Aseptic technique should be strictly maintained. The indication for the injection should be clearly documented. When glucocorticosteroids are injected into small joints and tendon spaces, the introduction of crystals into the subcutaneous tissue and adipose tissue should be avoided. The intramuscular administration of depot glucocorticosteroids should be avoided. Patients should be informed of the risk of infection and/or tissue atrophy, as well as of alternative forms of treatment.

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Year:  2012        PMID: 22787504      PMCID: PMC3394381          DOI: 10.3238/arztebl.2012.0425

Source DB:  PubMed          Journal:  Dtsch Arztebl Int        ISSN: 1866-0452            Impact factor:   5.594


  48 in total

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8.  Plantar fat pad atrophy after corticosteroid injection for an interdigital neuroma: a case report.

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9.  Necrotizing conjunctival ulceration following subconjunctival depot methylprednisolone injection.

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10.  Safety and efficacy of long-term intraarticular steroid injections in osteoarthritis of the knee: a randomized, double-blind, placebo-controlled trial.

Authors:  Jean-Pierre Raynauld; Chris Buckland-Wright; Rupert Ward; Denis Choquette; Boulos Haraoui; Johanne Martel-Pelletier; Imad Uthman; Visithan Khy; Jean-Luc Tremblay; Carole Bertrand; Jean-Pierre Pelletier
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  15 in total

1.  [Therapeutic strategies for joint infections].

Authors:  U-J Gerlach
Journal:  Chirurg       Date:  2018-02       Impact factor: 0.955

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4.  Low-dose analgesic radiotherapy is a real alternative.

Authors:  Ralph Mücke; Oliver Micke; Ulrich Schäfer; Michael Heinrich Seegenschmiedt
Journal:  Dtsch Arztebl Int       Date:  2013-01-07       Impact factor: 5.594

5.  In reply: Low-dose analgesic radiotherapy is a real alternative.

Authors:  Christian Holland
Journal:  Dtsch Arztebl Int       Date:  2013-01-07       Impact factor: 5.594

Review 6.  Non-Specific Low Back Pain.

Authors:  Jean-François Chenot; Bernhard Greitemann; Bernd Kladny; Frank Petzke; Michael Pfingsten; Susanne Gabriele Schorr
Journal:  Dtsch Arztebl Int       Date:  2017-12-25       Impact factor: 5.594

7.  The field size matters: low dose external beam radiotherapy for thumb carpometacarpal osteoarthritis : Importance of field size.

Authors:  Alexander Kaltenborn; Elke Bulling; Mirko Nitsche; Ulrich Martin Carl; Robert Michael Hermann
Journal:  Strahlenther Onkol       Date:  2016-06-14       Impact factor: 3.621

Review 8.  [Tendinopathies of the shoulder and elbow].

Authors:  Nael Hawi; Emmanouil Liodakis; Maximilian Petri; Christian Krettek; Rupert Meller
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Review 9.  Review of cooled radiofrequency ablation utilization for the treatment of symptomatic advanced knee arthritis and total knee arthroplasty.

Authors:  Andrew Tran; Felix M Gonzalez
Journal:  Skeletal Radiol       Date:  2022-04-25       Impact factor: 2.199

Review 10.  [Management of joint empyema].

Authors:  Julian Brand; Thomas Neubauer; Mohamed Omar
Journal:  Unfallchirurg       Date:  2021-12-07       Impact factor: 1.000

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