| Literature DB >> 22787501 |
Mi Jung Kim1, Myoung Chong Lee, Jae-Hong Lee, Sun Ju Chung.
Abstract
BACKGROUND: Neurologic manifestations of primary Sjögren's syndrome (PSS) have been reported to vary from sensory polyneuropathy to encephalopathy or psychiatric problems. However, marked cerebellar degeneration associated with PSS has rarely been reported. CASE REPORT: We describe a patient with Sjögren's syndrome who exhibited rapidly progressive cerebellar ataxia, nystagmus, cognitive decline, and psychiatric problems. Brain magnetic resonance imaging revealed marked atrophy of the cerebellum, and (18)F-fluorodeoxyglucose positron-emission tomography demonstrated glucose hypometabolism of the cerebellum.Entities:
Keywords: Sjögren's syndrome; ataxia; cerebellar degeneration; cognitive impairment
Year: 2012 PMID: 22787501 PMCID: PMC3391622 DOI: 10.3988/jcn.2012.8.2.155
Source DB: PubMed Journal: J Clin Neurol ISSN: 1738-6586 Impact factor: 3.077