Literature DB >> 22787501

Cerebellar degeneration associated with Sjögren's syndrome.

Mi Jung Kim1, Myoung Chong Lee, Jae-Hong Lee, Sun Ju Chung.   

Abstract

BACKGROUND: Neurologic manifestations of primary Sjögren's syndrome (PSS) have been reported to vary from sensory polyneuropathy to encephalopathy or psychiatric problems. However, marked cerebellar degeneration associated with PSS has rarely been reported. CASE REPORT: We describe a patient with Sjögren's syndrome who exhibited rapidly progressive cerebellar ataxia, nystagmus, cognitive decline, and psychiatric problems. Brain magnetic resonance imaging revealed marked atrophy of the cerebellum, and (18)F-fluorodeoxyglucose positron-emission tomography demonstrated glucose hypometabolism of the cerebellum.
CONCLUSIONS: Our PSS patient exhibited a progressive course of cerebellar syndrome, as evidenced by cerebellar atrophy on serial brain images.

Entities:  

Keywords:  Sjögren's syndrome; ataxia; cerebellar degeneration; cognitive impairment

Year:  2012        PMID: 22787501      PMCID: PMC3391622          DOI: 10.3988/jcn.2012.8.2.155

Source DB:  PubMed          Journal:  J Clin Neurol        ISSN: 1738-6586            Impact factor:   3.077


  29 in total

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8.  Progressive cerebellar degeneration revealing Primary Sjögren Syndrome: a case report.

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