Literature DB >> 22787187

Musculoskeletal involvement of syphilis--a forgotten lesson.

Jesus Vallejo Gomez1, Szabolcs Lajos Molnar, Sami Mansour Val, Rafael Gracia Arnal.   

Abstract

Syphilis is a sexually transmitted disease with a myriad of presentation and called 'the great impostor' for the variety of the symptoms. As a venereal disease it is transmissible mainly by sexual contact with infectious lesions but can spread by blood contamination. Without treatment it progresses through early and late syphilis. Since the introduction of penicillin its prevalence has strongly dropped but was never eradicated entirely. As the frequency and the progression are largely controlled there are several symptoms which are not common and can be a difficult differential diagnostic problem nowadays. The authors present a case where decades passed between the primary event and the actual hospitalisation with fever of unknown origin and coexistent swollen joint deformities. The patient was not treated entirely from his primary event and later, psoriasis was settled as a diagnosis, which was the cause of neglecting the secondary phase's skin lesions.

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Year:  2012        PMID: 22787187      PMCID: PMC3417008          DOI: 10.1136/bcr.11.2011.5142

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  8 in total

1.  IUSTI: 2008 European Guidelines on the Management of Syphilis.

Authors:  P French; M Gomberg; M Janier; B Schmidt; P van Voorst Vader; H Young
Journal:  Int J STD AIDS       Date:  2009-05       Impact factor: 1.359

2.  Syphilis in the United States: an update for clinicians with an emphasis on HIV coinfection.

Authors:  Nicola M Zetola; Joseph Engelman; Trevor P Jensen; Jeffrey D Klausner
Journal:  Mayo Clin Proc       Date:  2007-09       Impact factor: 7.616

Review 3.  [Sexually transmitted infections: epidemiology and control].

Authors:  M Díez; A Díaz
Journal:  Rev Esp Sanid Penit       Date:  2011

Review 4.  Psoriatic arthritis.

Authors:  J M Moll; V Wright
Journal:  Semin Arthritis Rheum       Date:  1973       Impact factor: 5.532

Review 5.  Syphilitic arthritis and osteitis.

Authors:  A J Reginato
Journal:  Rheum Dis Clin North Am       Date:  1993-05       Impact factor: 2.670

6.  Unsuspected syphilitic hepatitis in a patient with low-grade proteinuria and abnormal liver function.

Authors:  E K Blair; R E Sedlack; J P Snyder; J M Lawson
Journal:  Mayo Clin Proc       Date:  1990-10       Impact factor: 7.616

7.  Is serological testing a reliable tool in laboratory diagnosis of syphilis? Meta-analysis of eight external quality control surveys performed by the german infection serology proficiency testing program.

Authors:  Iris Müller; Volker Brade; Hans-Jochen Hagedorn; Erich Straube; Christoph Schörner; Matthias Frosch; Harald Hlobil; Gerold Stanek; Klaus-Peter Hunfeld
Journal:  J Clin Microbiol       Date:  2006-04       Impact factor: 5.948

Review 8.  Syphilis. A tale of twisted treponemes.

Authors:  J L Flores
Journal:  West J Med       Date:  1995-12
  8 in total

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