| Literature DB >> 22785471 |
Momoe Iha1, Miki Soma, Sho Sato, Yuki Mori, Saiko Sugawara, Kano Kasuga, Ikuo Kojima, Satoshi Yamada, Shujiro Sakaki, Masayuki Kobayashi.
Abstract
Embryoid bodies were prepared from mouse embryonic stem cells expressing exogenous EGAM1C to analyze their ability to differentiate toward terminally differentiated cell types. The generation of cardiomyocytes was severely suppressed in Egam1c transfectants without upregulation of Nkx2-5, a crucial gene for cardiomyogenesis. These results indicate that EGAM1C is capable of affecting terminal differentiation in mouse embryonic stem cells.Entities:
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Year: 2012 PMID： 22785471 DOI： 10.1271/bbb.120146
Source DB: PubMed Journal: Biosci Biotechnol Biochem ISSN： 0916-8451 Impact factor: 2.043