OBJECTIVE: Occupational exposure to hand-transmitted vibration can result in damage to nerves and sensory loss. The goal of this study was to assess the frequency-dependent effects of repeated bouts of vibration on sensory nerve function and associated changes in nerves. METHODS: The tails of rats were exposed to vibration at 62.5, 125, or 250 Hz (constant acceleration of 49 m/s2) for 10 days. The effects on sensory nerve function, nerve morphology, and transcript expression in ventral tail nerves were measured. RESULTS: Vibration at all frequencies had effects on nerve function and physiology. However, the effects tended to be more prominent with exposure at 250 Hz. CONCLUSION: Exposure to vibration has detrimental effects on sensory nerve function and physiology. However, many of these changes are more prominent at 250-Hz exposure than at lower frequencies.
OBJECTIVE: Occupational exposure to hand-transmitted vibration can result in damage to nerves and sensory loss. The goal of this study was to assess the frequency-dependent effects of repeated bouts of vibration on sensory nerve function and associated changes in nerves. METHODS: The tails of rats were exposed to vibration at 62.5, 125, or 250 Hz (constant acceleration of 49 m/s2) for 10 days. The effects on sensory nerve function, nerve morphology, and transcript expression in ventral tail nerves were measured. RESULTS: Vibration at all frequencies had effects on nerve function and physiology. However, the effects tended to be more prominent with exposure at 250 Hz. CONCLUSION: Exposure to vibration has detrimental effects on sensory nerve function and physiology. However, many of these changes are more prominent at 250-Hz exposure than at lower frequencies.
Authors: Stacey Waugh; Michael L Kashon; Shengqiao Li; Gerome R Miller; Claud Johnson; Kristine Krajnak Journal: J Occup Environ Med Date: 2016-04 Impact factor: 2.162
Authors: K Krajnak; S Waugh; C Johnson; R G Miller; D Welcome; X Xu; C Warren; S Sarkisian; M Andrew; R G Dong Journal: J Toxicol Environ Health A Date: 2015
Authors: Kristine M Krajnak; Stacey Waugh; Claud Johnson; G Roger Miller; Xueyan Xu; Christopher Warren; Ren G Dong Journal: Ind Health Date: 2013-09-27 Impact factor: 2.179